Flashcards in Type 2 diabetes Deck (3)
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1
Q
What is the aetiology for T2DM?
A
• Reduced insulin secretion ± increased insulin resistance
• Other possible causes
o Drugs: steroids, anti-HIV drugs, newer anti-pyschotics and thiazides
o Pancreatic: pancreatitis, surgery, trauma, pancreatic destruction, pancreatic CA
o Hormonal: Cushing’s syndrome, acromegaly, phaeochromocytoma, hyperthyroidism, pregnancy
o Others congenital lipodystrophy and glycogen storage disease
2
Q
What are the symptoms of hyperglycaemia?
A
o Polyuria o Polydipsia o Unexplained weight loss o Visual blurring o Genital thrush o Lethargy
3
Q
What is the treatment algorithm for T2DM?
A
- METFORMIN OR sulfonylurea/a-glucosidase inhibitor
- SULFONYLUREA OR metformin/a-glucosidase inhibitor/DPP-4 inhibiotor/thiazolidinedione
- BASAL INSULIN/PRE-MIX OR a-glucosidase inhibitor/DPP-4 inhibiotor/thiazolidinedione OR GLP-1 agonist
- BASAL + MEAL TIME INSULIN