UNIT 3 objective 3: addressing risks inherent to extemporaneous compounding

Question 1

what are some mistakes that can be made with extemporaneous compounding that can affect safety and efficacy?

Answer 1

1. wrong calculations
2. preparation steps
3. potential for contamination

Question 2

what are the 3 most vulnerable populations that use extemporaneous compounding?

Answer 2

1. neonates/infants/young children
2. people who cannot communicate
3. animals

Question 3

if an oral solution is compounded from an IR tablet or capsule , what is assumed?

Answer 3

the PK/bioavailability of the product will be the same or similar

Question 4

if an oral solution is compounded from a sustained release formulation, what is assumed?

Answer 4

the PK/bioavailability will be different

Question 5

suspended particles have _____ intimate contact with the vehicle

Answer 5

less

Question 6

if stability data isn’t known what should you assume what the BUD is?

Answer 6

14 days

Question 7

suspensions are easier to _________ without extensive experimentation

Answer 7

flavor/sweeten