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Flashcards in Unit 4 Deck (37):
1

what type of CA occurs in the liver

primary
secondary

2

which type of liver cancer is more common and why

secondary dt livers inc size, perf, portal drainage

3

2 types of primary liver ca

hepatocellular carcinoma
cholangiocarcinoma

4

how much of primary liver ca does hepatocellular carcinoma make up

90%

5

where does hepatocellular carcinoma originate

hepatocytes

6

2 main ets of hepatocellular carcinoma

chronic liver disease
environmental toxins

7

why may chronic liver disease predispose you to hepatocellular carcinoma

viruses in host cell may alter cell dna -> ca

8

mnfts of hepatocellular carcinoma

insidious onset
similar mnfts to preceeding liver disease
mnfts are often masked if CLD is present

9

what is the prognosis for hepatocelluar carcinoma

poor, cancer is usually well progressed when dx

10

if hepatocellular carcinoma is detected early, what is the tx

partial hepatectomy

11

tx for late dx hepatocellular carcinoma

palliatve care, chemo, radiation

12

what is another class of hepatocellular carcinoma

hepatic adenoma

13

which population has inc risk for hepatic adenoma

inc in 20-30 yo females on BCP

14

where does hepatic adenoma arise from

own hepatocytes and blood supply

15

risk of hepatic adenoma

can ruputre -> hemmor

16

tx for hepatic adenoma

stop BCP and dec H that promotes growth

17

whats the prognosis for hepatic adenoma

good

18

where does cholangiocarcinoma originate

bile duct and epithelial tissue

19

who has inc predispostion for cholangiocarcinoma

pts with chronic duct inflm

20

where are secondary tumors from

identified primary malignancy in colon, lung, breast

21

mnfts of secondary tumors in liver

non spec, those of CLD (jaundice, unexplained wt loss, anorexia, fever, hepatomegaly)

22

whats important about the non spec mnfts of secondary tumors in liver

fever in absense of infc
unexplained weight loss

23

whats the prognosis for 2nd growth in liver

poor, 3-6 months to live

24

tx for secondary tumor growth in liver

palliative care, sx, support

25

who has inc risk for pancreatic ca

men, smoker, black people

26

what is the mortality rate for pancreatic ca

90% in first year

27

what type of cancer makes up 90% of pancreatic ca cases

adenoma (duct glandular epithelium

28

What is the leading cause of Ca death

pancreatic cancer

29

et of pancreatic cancer

unclear

30

what is pancreatic cancer linked to

smoking
alcohol
age
poor diet

31

what are predispostions to pancreatic cancer

DM
chronic pancreatitis (not acute)

32

why is age linked to pancreatic ca

rt cumulative exposure to environmental triggers -> damage and genetic mutation

33

mfnts of pancreatic ca

dt mass taking up space in pancreas, causing inc P on ducts
jaundice, unexplained wt loss,

34

what is a classic mnft of pancreatic ca

abdm pain

35

dx pancreatic ca

US, CT

36

what is said about the pancreatic tumor after dx

it has normally already metastisized

37

tx for pancreatic ca

pain control
sx if early
palliative care
no chemo