Unit 4: Mood Disorders, Mood Stabilizers, and ADHD Flashcards Preview

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Flashcards in Unit 4: Mood Disorders, Mood Stabilizers, and ADHD Deck (46):
1

L1: Mechanism of Action? SSRIs

5HT reuptake inhbition

2

L1: Mechanism of Action? SNRIs

5HT + NE reuptake inhibition

3

L1: Name the most common MAOI.

Phenelzine

4

L1: Sex Demographics: _______ attempt more suicides; more ______ complete suicides.

Women; men

5

L1: Which pharmacologic agent? Narrow therapeutic index antimanic agent

Lithium

6

L2: Females tend to have more ______ symptoms in ADHD.

inattentive

7

L2: Mechanism of Action? Bupropion

NE + DA reuptake inhibition

8

L2: Mechanism of Action? Lithium

Unclear; G-protein pathways

9

L2: Mechanism of Action? MAOIs

Blocks degradation of NE and 5HT

10

L2: Mechanism of Action? Mirtazapine

Presynaptic alpha-2 antagonist (increases NE release)

11

L2: Mechanism of Action? Trazodone

5HT reuptake inhibition with 5HT antagonism

12

L2: Mechanism of Action? Tricyclic Antidepressants

NE +/- 5HT reuptake inhibition

13

L2: Mechanism of Action? Valproate

VSSC inhibition

14

L2: Name 2 SNRIs.

Venlafaxine, Duloxetine

15

L2: Name the most common TCA.

Amitriptyline

16

L2: Name the two most common stimulants used in the treatment of ADHD.

d-amphetamine (Adderall), methylphenidate (Ritalin)

17

L2: Which bipolar disorder pharmacologic agent? Anti-manic agents, reasonable safety/effectiveness, risk of metabolic effects/weight gain, expensive

Atypical Antipsychotics

18

L2: Which bipolar disorder pharmacologic agent? Anti-manic, anti-depressant, and reasonable prevention

Lithium

19

L2: Which bipolar disorder pharmacologic agent? Individualized treatment based on weight

Divalproex

20

L2: Which bipolar disorder pharmacologic agent? Not effective as preventative agent, sedation, not effective in bipolar depression

Divalproex

21

L2: Which bipolar disorder pharmacologic agent? Toxic/lethal in overdose

Lithium

22

L2: Which bipolar disorder pharmacologic agent? Tremor, taste dysfunction, thirst, cognitive dulling

Lithium

23

L2: Which class of antidepressants? Associated with Tyramine reaction

MAOIs

24

L2: Which class of antidepressants? Can cause anxiety and aggravation of psychosis

Bupropion

25

L2: Which class of antidepressants? Can cause hypertension and anxiety

SNRIs

26

L2: Which class of antidepressants? Causes sedation and antimuscarinic effects

TCAs

27

L2: Which class of antidepressants? Contraindicated in patients with seizure disorders or eating disorders

Bupropion

28

L2: Which class of antidepressants? Drowziness, dizziness, nausea, agitation

Trazodone

29

L2: Which class of antidepressants? EKG abnormalities that can lead to suddent death in overdose

TCAs

30

L2: Which class of antidepressants? Increased diastolic blood pressure

SNRIs

31

L2: Which class of antidepressants? Inhibits CYP450 enzymes

SSRIs

32

L2: Which class of antidepressants? Liver damage, hypertensive crisis when used with certain drugs

MAOIs

33

L2: Which class of antidepressants? May be useful in insomnia, rapid anti-anxiety effect, low incidence of sexual side effects

Mirtazapine

34

L2: Which class of antidepressants? More effective in severe depression

TCAs

35

L2: Which class of antidepressants? No sexual side effects and weight neutral

Bupropion

36

L2: Which pharmacologic agent? Effective for prevention of manic and depressive episodes in bipolar disorder

Lithium

37

L2: Which psychiatric diagnosis? May be associated with neuroendocrine dysfunction with disinhibition of HPA axis.

Depression

38

L3: Mechanism of Action? Electroconvulsive Therapy (ECT)

Increases activity of rate-limiting enzymes in 5HT and NE synthesis

39

L3: Name 3 SSRIs.

Fluoxetine, Paroxetine, Escitalopram

40

L3: Name the three cardinal signs of ADHD.

Excessive inattention, hyperactivity, impulsivity

41

L3: SIGECAPS

Sleep, Interest, Guilt, Energy, Concentration/Cognition, Appetite, Psychomotor, Suicidal ideation

42

L3: Which class of antidepressants? Causes orthostatic/postural hypotension

TCAs, MAOIs

43

L3: Which class of antidepressants? Flu-like or neurologic withdrawal symptoms

SSRIs, SNRIs

44

L3: Which class of antidepressants? Hyperthermia, myoclonus, muscle rigidity, and rapid changes in mental status and vital signs when administered with other select agents

SSRIs, MAOIs

45

L3: Which class of antidepressants? Seizures in overdose

TCAs, Bupropion

46

L4: Name the 4 treatments for bipolar depression in order from best to worst.

Quetiapine, lamotrigine, olanzapine/fluoxetine, lithium