Upper GI Tract Structure and Function Flashcards

1
Q

Why chew?

A

Prolong taste experience
Defence against resp. failure

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2
Q

How is chewing controlled voluntary?

A

Somatic nerves - skeletal muscles of mouth and jaw

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3
Q

Explain chewing controlled by reflex

A

Contraction of jaw muscles then pressure of food against gums, hard palette and tongue - mechanoreceptors - inhibition of jaw muscles so reduced pressure - contraction etc.

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4
Q

What are some main structures in the mouth?

A

Parotid duct
Parotid gland
Ducts of sublingual gland
Sublingual gland
Submandibular gland

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5
Q

What glands secrete saliva?

A

Parotid
Submandibular
Sublingual

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6
Q

What is saliva made up of?

A

Water, Mucins, Alpha amylase, electrolytes and lysozymes

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7
Q

Why is water in saliva?

A

Softens, moistens, dilutes particles
Acts as solvent

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8
Q

Why is mucins in saliva?

A

Major glycoprotein component
Lubricant function
Mucins + water is mucus

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9
Q

Why is alpha amylase in saliva?

A

Catalyses the breakdown of polysaccharides (starch and glycogen) into disaccharides and glucose

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10
Q

Why is electrolytes in saliva?

A

Tonicity and pH

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11
Q

Why is lysozymes in saliva?

A

Bactericidal so cleaves polysaccharide component of bacteria cell wall

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12
Q

How is salivary secretion controlled?

A

Parasympathetic and sympathetic
Both stimulatory

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13
Q

Explain the parasympathetic control of salivary secretion

A

Cranial nerves - facial (7) and glossopharyngeal (9)
Stimulation causes profuse watery salivary secretion

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14
Q

Explain sympathetic control of salivary secretion

A

Stimulation causes small volume and viscous saliva
High mucus content then alpha 1 adrenoreceptors
High amylase content then alpha 2 adrenoreceptors

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15
Q

Explain the reflex control of salivary secretion

A

Pressure of food in mouth activates chemoreceptors and pressure receptors

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16
Q

What causes lubrication of the oesophagus?

A

Submucosal mucous glands that secrete mucus out of ducts

17
Q

Explain the muscularis externa of the oesophagus

A

Upper 1/3 is skeletal muscle
Lower 2/3 is smooth muscle

18
Q

What is the function if the upper and lower oesophageal sphincters?

A

Regulate movement of material into and out of oesophagus

19
Q

Describe the oral phase of swallowing

A

Voluntary
Bolus pushed to back of mouth by tongue

20
Q

Describe the pharyngeal phase of swallowing

A

Presence of bolus causes sequence of reflex contractions of pharyngeal muscles
Co-ordinated by medulla
Soft palette reflected back and upwards

21
Q

Describe what happens when bolus approaches oesophagus?

A

Upper oesophageal sphincter UOS relaxes and epiglottis covers opening to larynx

22
Q

What happens when food has entered the oesophagus?

A

UOS contracts so prevention of food reflux

23
Q

Explain the oesophageal phase of swallowing

A

Propulsion of bolus to stomach
Peristaltic wave sweeps along entire oesophagus
Propelled to stomach in about 10 seconds

24
Q

What happens as bolus nears stomach?

A

Lower oesophageal sphincter (LOS) relaxes so bolus can enter stomach

25
Explain receptive relaxation of stomach
Initiated following relaxation of LOS and entry of bolus into stomach Vagal reflexes - relaxation of thin smooth muscle of gastric fundus and body
26
How much is stomach volume?
50ml to 1500ml
27
What are the functions of the stomach?
Temporary store of ingested material Dissolve food particles and initiates digestion Control delivery to small intestine Sterilisation Produce intrinsic factor
28
Describe the anatomy of the stomach in order
Oesophagus - gastroesophageal opening - cardiac region - fundus - body - pyloric region - pyloric opening
29
What are the layers of stomach tissue?
Serosa Muscularis externae Submucosa and mucosa Lumen surface
30
What are the 3 layers of the stomach muscularis externae?
Longitudinal Circular Oblique