Upper Respiratory Pathogens II Flashcards Preview

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Flashcards in Upper Respiratory Pathogens II Deck (39):
1

What are causative agents of conjunctivis

haemophilus influenzae
s. pneuomnia
moraxella lacunata, enterobacteria, and neisseria gonorrheea

2

Features of haemophilus influenza

very small gram negative rod

3

Features of streptococcus pneumoniae

gram positive, encapsulated

4

Pathogenesis of conjunctivis

mostly inflammatory response to the invading organisms

5

What is the most common causative agents of conjunctivis

haemophilus influenzae
s. pneumoniae

6

Prevention of conjunctivis

hand washing
don't rub eyes
don't use common towels

7

How do you treat conjunctivis

gentamicin or ciprofloxacin eyedrops

8

Symptoms of otitis media/sinusitis

throbbing ache of middle ear infection, decreased hearing

9

Common agents of otitis media/sinusitis

haemophilus influenza
streptococcus pneumoniae

10

What age group is most likely to get otitis media/sinusitis

early childhood

11

How to prevent otitis media/sinustis

don't use pacifiers beyond age 2

12

What are some things that could put you at greater risk of otisis media/sinusitis

viral infections
irriants like pollen, smoke, and pollution

13

Treatment of otisis media

ampicillin therapy
surgically remove enlarged adenoids
eustachian tubes

14

Major virulence factor in h. influenzae

antiphagocytic polysaccharid capsule

15

How do you treat h. influenzae infection

broad spectrum cephalosporins

16

How do you prevent h. influenzae infection

vax

17

What type of vaccine does h. influenzae have

conjugated vaccine

18

Can you treat h. influenza prophylaxtically?

yes

19

What do you use to eliminate the carriage of h. influenzae type b in children at high risk

rifampin

20

Features of chlamydia

possess inner and outer membranes
contain both DNA and RNA
posses prokaryotic ribosomes
synthesize their own proteins, nucleic acids and lipds

21

How is chlamydia different from other bacteria

can form both metabolically inactive but infectious forms - elementary bodies
and metabolically active noninfectious forms - reticulate bodies

22

What diseases is chlamydia trachomatis responsible for

trachoma, adult inclusion conjuctivis, neonatal conjunctivitis, infact pneuomina, urogenital infections

23

What are the receptors for c. trachomatis EB's

noncilitated columnar, cuboidal, and transitional epithelial cells

24

Clinical manifestations of c. trachomatis infections are caused by what

direct destruction of cells during replication
host inflammatory response

25

Trachoma

chronic
start as follicular conjuctivis
conjunctiva becomes scarred, eyelids turn inward
eventually blidness

26

adult inclusion conjuctivis symptoms

mucopurulent discharge, keratitis, corneal infiltrates, some vascularization

27

neonatal conjuctivis

happens at birth
get swollen eyelids, hyperemia, copious purulent discharged.

28

infant pneumonia

2-3 weeks after birth
rhinitis, then staccato cough, infants have bronchitis, afebrile throughout clinical illness

29

How can you diagnosis c. trachomatis

cytologic, serologic, or culture findings
antigen
molecular probes

30

What are the BEST ways to diagnosis c. trachamoatis

PCR or antigen detection

31

How do you treat ocular and genital chlamydia infections in adults

azithromycin or doxycycline for 7 days

32

How do you treat newborn conjuctivis and pneumonia

erythromycin for 10-14 days

33

What diseases does c. pneumoniae cause

pneumonia, bronchitis, sinusitis

34

How do you diagnosis c. pneumoniae

nucleic acid amplication, PCR

35

How do you treat c. pneumoniae

macrolides, tetracyclines, or levofloxacin for 10-14 days

36

What happens to pts with c. psittaci

edema, thickening of alveolar wall, inflitration of macrophages, necrosis, possible hemophages

37

What are some symptoms of people with c. psittaci

cyanosis and anoxia

38

What's the give away that someone has c. psittaci

they handle birds

39

How can you differentiate between bacterial and viral conjunctivis

bacteria usually have more pus and inflammation