Urethral Obstruction Flashcards
What sex of dogs and cats are most commonly affected by urethral obstruction?
Males
Why are males more prone to urethral obstruction than females?
Complicated path and narrow lumen of male urethra
What are physical obstructions that can occur in the urethra?
Urolith, neoplasia, stricture, mucosal plug
What kind of mechanical obstruction occurs in the urethra?
Severe urethral spasma
What is the most important life-threatening e-lyte imbalance assoc. w/urethral obstruction?
Hyperkalemia
Why does urethral obstruction cause hyperkalemia?
Decreased renal potassium excretion and extracellular shift d/t acidosis
How does hyperkalemia affect cardiac myocytes?
Affects resting membrane potential and eventually disables depolarization of cells
What ECG changes are assoc. w/hyperkalemia?
Bradycardia, tall/narrow T waves, wide QRS, decreased/absent P waves
How does 0.9% NaCl IVFT help treat hyperkalemia?
Dilutes serum potassium
How does IV Ca gluconate help treat hyperkalemia?
Restores membrane potential and re-establishes normal depolarization
Does IV Ca gluconate lower K+ levels?
NO
How does IV dextrose and regular insulin help treat hyperkalemia?
Moves potassium back into cells
Why should you never give insulin alone to a hyperkalemic patient?
Can result in hypoglycemia and seizures
How does sodium bicarb help treat hyperkalemia?
Shifts potassium back into cells as pH increases
How does metabolic acidosis result from urethral obstruction?
Kidneys unable to excrete H+ ions