Urinary Tract Infection Flashcards

1
Q

Tell me about Urinary tract infection

A

is the commonest bacterial infection managed in GP.

3% of F aged 20 then raises 1% for each decade

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2
Q

What is covered under the umbrella of urinary tract infection

A

Cystitis

Pyelonephritis

urethritis

Prostitis

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3
Q

Symptoms of Cystitis

A

Cystitis is the infection of the bladder

Frequency

Dysuria

Urgency (inflamed bladder wall)

Haematuria

Suprapubic pain

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4
Q

What is micturition

A

is the ejection of urine from the urinary bladder through the urethra to the outside of the body.

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5
Q

UTI symptoms

A
frequency
hesitancy
urgency
dribbling
blood (Haematuria)
Dysuria
incontinence, fever.
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6
Q

What is nocturia

A

Wake up and pass urine at night

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7
Q

Symptoms of prostitis

A

flu-like symptoms

backache

swollen/tender prostate on PR

few urinary symptoms

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8
Q

Signs of UTI

A
  • Fever
  • Abdo or loin tenderness
  • Foul smelling urine and cloudy
  • Distended bladder maybe
  • Enlarged prostate
  • Vaginal discharge
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9
Q

How to investigate UTI

A

• Urine dip stick
• MC&S urine + culture
• USS
Blood test –> FBC and U&E

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10
Q

What is cytoscopy

A

Tube into urethra to bladder to see inside

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11
Q

What will you look for in suspected UTI dip stick

A

if nitrates or leukocytes are positive then most likely it is of bacterial cause

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12
Q

In UTI when would you send sample to MC&S urine and culture

A

o Send if dip -ve but symptomatic and male child

o Or pregnant, immunocompromised, or VERY ILL

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13
Q

In UTI, when is further imaging or cytoscopy is indicated

A

o Persistent not responding to Tx
o History of renal tract disease
o Haematuria
o Men with 2 or more episodes in 3 months. Or Any men with obstruction suggestions

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14
Q

Differentials of UTI

A

Urethritis caused by an STI

Reiter’s syndrome - arth+conjuc+urethritis occur at same time

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15
Q

Causative organisms of UTI

A

Escherichia coli from GI tract is 75%
enterobacter (Proteus mirabilis, Klebsiella pneumoniae)
Staphylococcus saprophyticus.

urethritis
Gonococcal (Gonorrohoea)
non-gonococcal

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16
Q

Medical Management of UTI

A

Abx therapy, start broad with trimethorpim initially and after MC&S give narrow according to results. Ideally treat with ABx for 3 days only

steps
trimethorpim, nitrofurantoin or Amoxicillin

cephalosporin or 2nd line co-amoxiclav

17
Q

Other lifestyle management of UTI

A

Lots of fluids

cranberry juice

18
Q

How to manage presisten or recurrent UTI

A

Look for other causes if MC&S is already done

Incomplete bladder emptying (prostatic disease, neurological problems)

Foreign body (catheter, stone)

Failure of host defences (diabetes, post-menopausal atrophic urethritis)

19
Q

Simple measure that may aid in preventing recurrent UTI

A

Fluid intake > 2 L/day

Regular complete bladder emptying

Good personal hygiene

Emptying of bladder before and after sexual intercourse

Cranberry juice.

20
Q

Tell me about acute pyelonephritis

A

It is an ascending infection from the bladder

rarely complicates into perinephric abscess or papillary necrosis

21
Q

Presentation of acute pyelonephritis

A

sudden onset pain on 1 or both loins +- radiation to the illiac fossaand suprapubic region

associated with fevers (more than 38) rigors, vomiting and hypotension

lumbar tenderness and guarding

dysuria because of cystitis involvement in 30%

22
Q

Differentials of acute pyelonephritis

A

acute appendicitis
diverticulitis
cholecystitis

23
Q

What findings you expect to see in a urine dipstick when acute pyelonephritis is suspected

A

Neutrophils and organisms (bacteria), with presensce of symptoms will confirm diagnosis

red cells

tubular epithelial cells in urine

24
Q

Why would you want to use renal tract USS or CT in acute pyelonephritis

A

to exclude perinephric collection and obstruction

25
Q

How to manage acute pyelonephritis

A

adequate fluid intake is necessary even if it is IV fluids

Abx treatment with first-line co-amoxiclav and ciprofloxacin for 7-14 days

26
Q

How to manage severe acute pyelonephritis

A

Severe cases require initial IV therapy, with a cephalosporin, quinolone or gentamicin

27
Q

What else you should do when managing acute pyelonephritis

A

Urine should be cultured during and after treatment.

28
Q

A 33 yr old F presents with fever and right sided flank pain for one day. Denies frequency, urgency, dysuria, or hematuria and bowel symptoms?

What is the most likely diagnosis

A

acute pyelonephritis

29
Q

Gram -ve vs gram +ve

A

blue +ve
more susceptible to Abx, penicillin and vancomycin Vgood
streptococcus, staphylcoccus, clostridium
steroptomycin and tetracyclines dnt do shit
red -ve
More resistant to Abx Penicillin and vancomycin Bad
E coli
H. influenzae
pesuedomonas
neisseria meningitidis
steroptomycin and tetracyclines killsem