Use, Misuse, Abuse, Addiction, & Dependency Deck (E1) Flashcards
(30 cards)
The objective definition of a drug is determined by…
Science
The subjective definition of a drug is determined by…
Whatever society deems a drug
Drugs are often discovered by { }, { }, or { } research. These methods can often overlap.
1) Nature
2) Accident
3) Medical/pharmaceutical
General term to describe how a drug is utilized, whether once or many times.
What is use?
Using a drug outside of its intended use.
What is misuse?
Broad term that describes uncontrolled use. “I can’t define it, but I know it when I see it.”
What is abuse?
A constellation of behaviors including uncontrolled use, drug seeking, and continued use in the face of harm.
What is addiction?
What is the strongest indicator of drug addiction?
Continued use in the face of harm
Physical phenomenon in which the body requires a drug to function “normally.”
What is dependence?
What is the KEY difference between physical and psychological dependence?
(HINT: symptoms)
Marked withdrawal symptoms (physical)
This condition occurs when you take too much of a drug.
What is overdose?
Dosage amount at which 50% of the population will experience the intended effect of a drug.
What is median effective dose (ED50)?
Dosage amount that will produce a toxic effect in 50% of a population.
What is median toxic dose (TD50)?
Dosage amount that will kill 50% of a population.
What is median lethal dose (LD50)?
The ratio of median effective dose (ED50) to median lethal dose (LD50).
What is therapeutic index (TI)?
The safety ratio is the { } of the therapeutic index.
Inverse
What is the difference between purity and potency?
1) Purity - how much of a drug is in a drug
2) Potency - compares drugs relative to each other based on amount needed to produce desired effect
What is the difference between drug action and effect?
1) Action - CONSISTENT biochemical process occurring after consuming a drug
2) Effect - INDIVIDUALIZED effects experienced by individual drug users
The time it takes for a drug’s initial concentration to reduce by half while in the body.
What is half-life?
What is the difference between acute and chronic effects?
1) Acute - relative, immediate
2) Chronic - long-term
This type of tolerance refers to what it takes to feel the effect of a drug. Dosage taken varies between people trying to get the intended effect of a drug, which is typically associated with usage history.
What is pharmacological tolerance?
This type of tolerance refers to a person’s ability to physically and mentally function under the influence.
What is behavioral tolerance?
An instance in which people can develop a tolerance to a drug without using it because of usage history with another similarly effective drug.
What is cross-tolerance?
This least effective route of administration.
What is oral?
