Uterine pathology Flashcards
(17 cards)
Causes of abnormal uterine bleeding in adolescnece?
Pregnancy/miscarriage
Endometritis
Bleeding disorders
Causes of AUB in reproductive life?
Pregnancy DUB Endometritis Polyps Hyperplasia Neoplasia etc etc
Causes of AUB post menopause
Atrophy Polyp Endometritis Carcinoma etc etc
Methods of assessing the endometrium?
Transvag ultrasound
Hysteroscopy
Methods of sampling endometrium?
Endometrial pipelle
Dilatation and curretage
What is DUB?
Irregular uterine bleeding that reflects a disruption in normal cyclic pattern of ovulatory hormonal stimulation
When does DUB occur?
At either end of repeoductive life
Describe DUB due to luteal phase insufficiency
Corpus luteumdoes not produce sufficient progesterone, or endometrium has poor response to progesterone
What is Chronic plasmacytic endometritis associated with?
PID
Presentation of endometrial polyps?
Usually asymptomatic, can present with bleeding or discharge
What is a molar pregnancy?
An abnormal form of pregnancy in which a non viable fertilised egg impants in the uterus or uterine tube.
Charateristic of molar pregnancy?
A mass with swollen chorionic villi
What is a complete mole?
Single or two sperm combining with egg which has lost DNA
Sperm reduplicared forming 46 chromosome. Only paternal DNA present
Partial mole?
Egg fertilised by two sperm or by one which reduplicates
Yields genotype 69XXY
Have both maternal and paternal DNA
Risk of hydatiform moles?
Higher risk of developing into choriocarcinoma (Malignant tumour of trophoblast) than partials
What is Adenomyosis?
Endometrial glands and stroma within the myometrium
Causes menorrhagia/dysmenorrhoea
What is leiomyoma?
Benign tumour of smooth muscle, may be found in locations other than uterus
Growth oestrogen dependant
