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Flashcards in UWorld-Blood Vessels Deck (9)
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what disease matches this histology: transmural inflammation with fibrinoid necrosis

polyarteritis nodosa


what disease for this histology: medial band-like calcification

Monckeburg's (medial calcific necrosis)


homogenous acellular thickening of arteriolar walls =?

hyaline arteriolosclerosis


onion-like thickening of arteriolar walls =?

hyperplastic arteriolosclerosis (can result from malignant HTN)


granulomatous inflammation of the media =?

temporal arteritis (or Takayasu's: use age and location of lesion to differentiate [temporal arteries vs. great vessels of aortic arch])


focal necrotizing granulomas in lung and upper airway as well as necrotizing glomerulonephritis =?

Wegener's (granulomatosis with polyangitis)


similar to Wegener's but without nasopharyngeal involvement, pauci-immune glomerulonephritis and palpable purpura =?

microscopic polyangitis


name some examples of leukoclastic vasculitis;
what is their characteristic histology

microscopic polyangitis, microscopic polyarteritis, hypersensitivity vasculitis (i.e. Rheumatoid arteritis);
characterized by fibrinoid necrosis


what do adenosine and ACh do to cardiac pacemaker cells

adenosine prolongs opening of K+ channels and blocks slow inward Ca2+ influx allowing for hyperpolarization of the cell and decreased rate of action potentials;
ACh acts similarly, but also decreases slow Na influx in addition to slow Ca2+ influx