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Flashcards in UWorld_7.27 Deck (44):
1

Sudden lower limb signs of arterial occlusion w/hx of recent MI ==> dx?

arterial embolism (from L heart s/p MI or atria w/afib)

2

Arterial thrombosis presentation

-insidious/gradual onset of sx of ischemia
-pulses usually diminished bilaterally

3

B-thalassemia minor presentation/management

-asx
-mild anemia + high RBC count
-low MCV
-Hb > 10
-no management needed

4

Delayed complication after blunt trauma/MVC

-diaphragmatic rupture; L>R
- ==> dilated loops of bowel in chest

5

Physiologic cause of sx of cardiac tamponade

-cardiac tamponade/pericardial effusion ==> shift of interventricular septum towards left ventricle
- ==> reduced left ventricular preload ==> reduced stroke volume/cardiac output

6

Older pt. w/bone pain, elevated alk phos, normal Ca ==> dx?

paget disease of bone

7

Paget disease of bone cause/sx

-2/2 osteoclast dysfxn ==> increased bone turnover
-bone pain/deformity
-@ skull: H/A. hearing loss
-@ spine: spinal stenosis, radiculopathy
-@ long bones: bowing, fx, arthritis

8

Imaging in paget disease of bone

-XR: osteolytic vs. lytic/sclerotic lesions
-bone scan: focal uptake increased

9

Tx of paget disease of bone

bisphosphonates

10

Colon cancer screening in IBD

-8yrs post-dx
-colonoscopy q1-2 yrs

11

Colon cancer screening in FAP

-colonoscopy 10 years b4 age dx of relative or @ 40
-repeat q3-5 yrs

12

Preconception initial screening for thalassemia

-non-african descent: CBC
-african descent: CBC + Hb electrophoresis

13

Digitalis/Digoxin toxicity arrhythmia

-digoxin ==> increased ectopy and vagal tone
- ==> atrial tachycardia w/AV block

14

Peripheral smear in sickle cell pt.

Howell Jolly bodies

15

Howell Jolly bodies ==> ?

asplenia (fxnl or actual)

16

Tx of ventricular tachycardia

-stable ==> IV amiodarone
-unstable ==> cardioversion

17

High-yield interventions that improve transitions of care

interventions that target PHARMACY PERSONNEL & HIGH-RISK PATIENTS

18

Cause of thrombocytopenia in SLE

immune-mediated peripheral destruction

19

Management of prolactinomas

-asx/micro ( no tx
-sx/macro(>10mm) ==>
1. DA agonists: cabergoline, bromocriptine
2. resection: if >3cm or increase in size while on tx

20

Primidone: MOA, use

-barbituate
-anticonvulsant, tx of essential tremor

21

Trihexyphenidyl: MOA, use

-MOA = anticholinergic
-tx of parkinsons; particularly in younger pt. w/tremor as primary sx

22

Evaluation of rapidly expanding head circumference in infant

- 6mo: CT vs. sedated MRI to spare radiation

23

Urine collection in children

-clean catch if out of diapers
-infants/toddlers in diapers ==> straight catheterization

24

anti-topoisomerase I ab association

systemic sclerosis

25

anti-mitochondrial ab association

primary biliary cirrhosis

26

ANCA association

polyangiitis (wegener's) = granulomatous vasculitis

27

Anti-smooth m. ab association

autoimmune hepatitis

28

Pulmonary edema impact on lung fxn

- ==> V/Q mismatch, increased A-a gradient, low lung compliance
-moderate supplemental o2 improves status

29

Presentation of hereditary angioedema

-noninflammatory edema of the face, limbs, and genitalia
-laryngeal edema ==> life threatening
-edema of intestines ==> colicky abdominal pain
-episodes follow infection, dental procedure, or trauma

30

Cause of hereditary angioedema

-C1 inhibitor deficiency, dysfxn, or destruction
- ==> elevated C2b and bradykinin

31

Bowel sounds in SBO

high-pitched

32

SBP vs. SBO

-SBP ==> vague abdominal pain, decreased bowel sounds, AMS (abnormal connect-the-numbers)
-SBO ==> N/V, high-pitched bowel sounds

33

RAIU in toxic multinodular goiter

patchy distribution

34

Language development @ 12 mo, 18 mo, 2 yrs

-12 mo: mama, dada + few other first words
-18 mo: 10-25 words
-2 yrs: 50+ words

35

Imaging in Alzheimer's disease

atrophy prominent @ temporal and parietal loves

36

dysphagia + regurgitation + chest pain w/emotional stress ==> dx?

-diffuse esophageal spasm/esophageal motility disorder
-relieved by nitrates

37

Features of intracerebral hemorrhage stroke

-hx uncontrolled HTN, coag, drug use
-sx progress @ min - hours
-focal neuro sx, then sx of ICP (vomiting, H/A, AMS)

38

Evaluation of ovarian mass + thickened endometrial stripe

-endometrial biopsy for concomitant malignancy

39

Tactile fremitus in pleural effusion

decreased

40

Tactile fremitus in consolidation

increased

41

Theophylline toxicity presentation

-CNS: H/A, insomnia, seizures
-GI: N/V
-cardiac arrhythmia

42

S. bovis bacteremia ==> ?

colonoscopy to evaluate for colon cancer

43

Pellagra

diarrhea, dermatitis, dementia

44

Ppx for varicella exposure in child

-immunized ==> observation
-unimmunized, immunocompetent ==> varicella vaccine
-unimmunized, immunocompromised ==> VZIG w/in 10 days of exposure