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Flashcards in Vasculitides Deck (16)
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1

What are the large vessel vasculitidies?

Temporal arteritis (giant cell arteritis)

Takayasu's arteritis

2

Temporal arteritis

Headache, eye pain/vision loss. Treat with steroids ASAP, then do temporal artery bx.

3

Takayasu's arteritis

Vasculitis of large vessels such as aorta. Leads to diminished peripheral pulses, hand claudication, discrepancies of BP readings. Classically in young Asian women. Tx: steroids, anti-HTN, surgery.

4

What are the medium vessel vasculitides?

Kawasaki's, GPA, EGPA, PAN

5

Features of Kawasaki's disease

Fever, conjunctivitis, stomatitis, rash, pericarditis/myocarditis. Tx with IVIG and aspirin!

6

GPA stands for

Granulomatosis with polyangiitis (artist formerly known as Wegener's)

7

GPA features

ANCA-assoc GN, lung, sinus

8

EGPA stands for

Eosinophilic granulomatosis with polyangiitis (artist formerly known as Churg-Strauss)

9

EGPA

p-ANCA assoc GN, asthma, eosinophilia

10

PAN stands for

Polyarteritis nodosa

11

Polyarteritis nodosa

p-ANCA assoc GN, affects all organ systems except NO lung involvement. Assoc with Hep B

12

What are the small vessel vasculitides?

Microscopic polyangiitis, Behceet's, hypersensitivity vasculitis

13

Microscopic polyangiitis

Affects kidney, skin, joints, lungs

14

Behcet's syndrome

Triad: oral apthous ulcers, genital ulcers, uveitis. Tx steroids

15

Treatment for ANCA assoc vasculitides?

Steroids, cyclophosphamide, rituximab

16

Buergers disease (thromboangiitis obliterans)

Classically in young male smokers. Causes ischemic claudication which can lead to gangrene. Must stop smoking!