vesicular diseases of the skin

Question 1

autoAb against bullous pemphigoid Ag BP180 and BP230

Answer 1

bullous pemphigoid

Question 2

• Most common bullous autoimmune disease

Answer 2

bullous pemphigoid

Question 3

does not involve mucosal surfaces; tense bullae arise in normal or erythematous skin

Answer 3

bullous pemphigoid

Question 4

subepidermal blister with eosinophils

Answer 4

bullous pemphigoid

Question 5

what is the only type of pemphigoid that involves mucosal surfaces

Answer 5

cicatricial pemphigoid

Question 6

Papules, vesicles, occasional bullae on erythematous, urticarial base on elbows and knees with pruritis

Answer 6

dermatitis herpetiformis

Question 7

which subepidermal vesicular disease is assoc’d with celiac disease

Answer 7

dermatitis herpetiformis

Question 8

clusters of jewels, widespread vesicles and bullae on trunk

Answer 8

Linear IgA bullous dermatosis

Question 9

PCT is associated with what liver pathology

Answer 9

Hep C

Question 10

tense bullae on normal skin on light exposed background

Answer 10

PCT

Question 11

Weakness of basement membrane bw dermis and epidermis; non scarring; on legs and feet

Answer 11

bullous diabeticorum

Question 12

dislodging of epidermis by lateral finger pressure near lesions, leading to erosion; assc’d with?

Answer 12

nikolsky sign; pemphigus vulgaris

Question 13

IF with ll surface IgG or C3; chicken wire

Answer 13

pemphigus vulgaris

Question 14

Vesicles & bullae replaced by crusting erosions resembling impetigo; found in flexural and intertriginous areas (axillae, groin, neck); due to defect in Ca pump

Answer 14

hailey haliey disease

Question 15

Multiple discrete scaling papules in seborrheic distribution on chest, back, ears, forehead, scalp, groin; due to defect in Ca pump

Answer 15

darier’s disease

Question 16

Middle age, males; occurs with heavy sweating/heat (bedridden patients); abrupt onset pruritic crops of lesions on trunk and extremities

Answer 16

grover’s disease