VIII - Skin Flashcards Preview

Histology > VIII - Skin > Flashcards

Flashcards in VIII - Skin Deck (36):
1

Outermost layer of integument, stratified squamous epithelial layer of ectodermal origin, devoid of blood vessels and consists of 4-5 layers

epidermis

2

Connective tissue layer of mesodermal origin below the epidermis and its basement membrane

dermis

3

Dermis: loose, comparatively cell-rich connective tissue, fills the hollows at the deep surface (dermal papillae) of the epidermis, capillaries are frequent, collagen fibers are finer

papillary layer

4

Dermis: appears denser and contains fewer cells, thick collagen fibers that aggregate into bundles

reticular layer

5

Layer of loose vascular connective tissue infiltrated by adipocytes

hypodermis

6

Skin: production of keratin protein, squamous epithelial cells

keratinocyte

7

Skin: important in formation of endogenous sunscreen, sound in basal layer and in hair follicles

melanocyte

8

Skin: epidermal dendritic cells, antigen presenting cells

Langerhan cells

9

Skin: serve as mechanoreceptors or a neuroendocrine function

Merkel cells

10

Disorder in which melanocytes are destroyed, autoimmune

Vitiligo

11

Disorder in which melanocytes are unable to synthesize melanin either due to abscence of tyrosinase activity or inability to take up tyrosine

Albinism

12

Skin Layers from most superficial

corneum, lucidum, granulosum, spinosum, basale

13

Skin Layers: superficial stratum layer consisting of 20-30 layers of dead, flat, anucleated and cornified/keratinized cells filled with keratin filaments (horny cells) embedded in a densematrix of proteins

Stratum Corneum

14

Skin Layers: spaces between cells are filled with lipids making a continuous membrane, protects against friction and water loss

Stratum Corneum

15

Skin Layers: 2-3 layers of transitional cells of flat eosinophilic anucleated cells, only found in regions of thick stratum corneum of palms and soles

Stratum Lucidum

16

Skin Layers: polygonal cells filled with basophilic keratohyaline granules, only 1 layer is seen in thin skin, multiple in thick skin

Stratum Granulosum

17

Part of stratum granulosum that produces a lipid-rich impermeable layer around cells

lamellar granules

18

Skin Layers: multilaminar layer of cuboidal-like cells that are bound together by numerous desmosomal junctions

Stratum Spinosum

19

Antigen presenting cells in stratum spinosum, contains Birbeck granules

Langerhan cells

20

Single layer of cuboidal to low columnar cells in contact with basement membrane, attached to the basal lamina via hemidesmosomes, mitotically active

Stratum Basale (Germinatum)

21

Cells in the stratum basale with intense mitotic activity

melanocytes, Merkel cells

22

Sensory Recetor Capsule: Merkel cells

unencapsulated

23

Sensory Recetor Capsule: free nerve endings

unencapsulated

24

Sensory Recetor Capsule: root hair plexuses

unencapsulated

25

Sensory Recetor Capsule: Meissner corpuscles

encapsulated

26

Sensory Recetor Capsule: lamellated (Pacinian) corpuscles

encapsulated

27

Sensory Recetor Capsule: Krause end bulbs

encapsulated

28

Sensory Recetor Capsule: Ruffini corpuscles

encapsulated

29

Simple branched acinar holocrine grands, found in the dermis except in the palms and soles, lubricate hair and cornified layers of the skin to minimize dessication

sebaceous glands

30

Sebaceous Glands: hairy areas

pilosebaceous unit

31

Sebaceous Glands: glabrous skin

sweat pores

32

Sudoriferous Glands

Sweat Glands

33

Sweat Glands: coiled tubular glands, in most areas of the skin, opens in skin surface, clear, odorless (H2O, NaCl), active throughout life, body temperature regulation (cholinergic), emotional sweating (adrenergic)

eccrine, merocrine

34

Sweat Glands: coiled tubular glands, axillary, areolar, anal, hair follicles, viscous, odorous, active at puberty, pheromones (adrenergic)

apocrine

35

When apocrine sweat or sebaceous glands are occluded and infected

Hidradenitis Suppurativa

36

Abnormal aggregation of cells that may be seen in squamous cell CA

keratin pearls