viral structure, RNA vs DNA, envelope?, pathogenesis, type of infection Flashcards Preview

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Flashcards in viral structure, RNA vs DNA, envelope?, pathogenesis, type of infection Deck (18):
1

orthomyoxyvirus

INFLUENZA

RNA virus

-ss, 8 segment genome

enveloped

pathogenesis = droplets and aerosol (undergoes antigenic shift/drift)

respiratory tract infection

2

paramyxovirus

RESPIRATORY SYNCYTIAL VIRUS (RSV) + measles, mumple, parainfluenza

RNA virus

-ss, linear genome

enveloped

pathogenesis = droplets (can be serious for infants)

respiratory tract infection

3

Reovirus

ROTAVIRUS

RNA virus

ds, 11 segment genome

non-enveloped

pathogenesis = fecal-oral (can be serious for infants)

gastroenteritis

4

Togavirus

RUBELLA

RNA virus

+ss, linear genome

enveloped

pathogenesis = droplets or vertical

*teratogenic*

rubella, congenital rubella syndrome

5

Flavivirus

WEST NILE VIRUS

RNA virus

+ss, linear genome

enveloped

pathogenesis = mosquitos (most infections are subclinical)

west nile fever, CNS infections

6

Rhabdovirus

RABIES

RNA virus

-ss, linear genome

enveloped

pathogenesis = animal bite (saliva)

*invariably fatal without post-exposure prophylaxis*

encephalitis

7

Picomavirus

ENTEROVIRUS

RNA virus

+ss, linear genome

non-enveloped

pathogenesis = droplets or fecal-oral (diverse family of viruses causing wide range of diseases)

respiratory infection; hand, foot and mouth disease; conunctivitis; CNS infections; myocarditis

8

Calicivirus

NOROVIRUS

RNA virus

+ss, linear genome

non-enveloped

pathogenesis = fecal-oral, food, water or aerosolization (seasonal epidemics)

gastroenteritis

9

Adenovirus

ADENOVIRUS

DNA virus

ds, linear genome

non-enveloped

pathogenesis = respiratory droplets or fecal-oral (wide # types associated with different diseases)

respiratory tract infections, gastroenteritis, conjunctivitis

10

Papillomavirus

HPV

DNA virus

ds, circular genome

non-enveloped

pathogenesis = contact transmission (persistent, high risk HPV infections can lead to cancer)

warts, various cancers

11

Herpes Virus

HSV-1

DNA virus

ds, linear genome

enveloped

pathogenesis = contact or vertical transmission (becomes latent inside neurons; periodic reactivation can occur in some people)

infection of skin and mucosa, eyes, CNS

12

Hepadnavirus

HEPATITIS B

DNA virus

ds/ss, circular genome

enveloped

pathogenesis = exposure to body fluids or vertical transmission

infects hepatocytes, requires reverse transcriptase for replication

hepatitis, cirrhosis, hepatocellular carcinoma

13

viruses with a human respiratory reservoir

influenza
parainfluenza
rhinovirus
coronavirus

14

viruses with a human mucosal reservoir

oral: HSV, epstein barr, CMV

genital: HIV, Hep B/C, HPV, HSV

15

viruses that have a fecal-oral environmental source

Hep A
rotavirus
norovirus

16

viruses that have a fomite environmental source

adenovirus

17

viruses transmitted by mosquito vector

dengue
chikungunya
west nile

18

viruses transmitted by an animal vector

rabies
LCMV