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Flashcards in Virology Deck (48):
1

Smallest RNA virus

Picornavirus

2

Smallest DNA virus

Parvovirus

3

Largest virus

Poxvirus

4

SS DNA virus

Parvovirus and Anello

5

DS RNA virus

Reovirus and Picobirnavirus

6

RNA can act as mRNA inside infected cell. Translation

(+) sense RNA

7

A reversible step in early phase of virus replication

Recognition & attachment

Protein needed- VAP

8

An obligatory step in early phase of virus replication

Uncoating

9

DNA virus that replicate in the cytoplasm

Poxvirus

10

Naked viruses released by

Cell lysis

11

Enveloped virus released by

Budding

12

Poxvirus that infects human

Variola
Vaccinia
Molluscum contangiosum

13

Most common MOT of smallpox

Inhalation

14

CASE:
From macules to vesicles to pustules to crusting, pink scars, appear at the same time, centrifugal (face and chest to distal)
Lab: Guarnieri bodies

Smallpox (Variola)

15

Laboratory generated virus,
Used for immunization

Vaccinia

16

Case:
Wartlike lesions, begin as papules and progress to umbilicated nodule

Lab: Henderson-Patterson bodies

Molluscum contagiosum

17

Fast growing and cytolytic
Latent in neurons

HSV, VZV (Alpha herpes virus)

18

Slow growing and cytomegalic
Latent in secretory glands and kidney

CMV, HHV 6 & 7 (Beta herpes virus)

19

Latent in lymphoid cells

Gamma herpes virus, EBV, HHV 8

20

HSV type which is the MOT is thru saliva
Cell to cell fusion
Causes infection above waist
Latent in trigeminal ganglia
Causes fatal encephalitis, gingivostomatitis

HSV1

21

HSV type transmitted thru sexual contact, vertical transmission
Cell to cell fusion
Infections manifested below wait
Latent in sacral ganglia
Cause meningitis

HSV2

22

Herpes labialis

HSV 1 & 2

23

Specific confirmatory test used in HSV

Tzanck test -Cowdry type A

24

DOC for HSV

Acyclovir

25

Cowdry type A inclusions

HSV, VZV

26

Case:
Macupapular to vesicular rash (teardrop on pink base)
Appear in Crops of different stages

Varicella (chicken pox)

27

Most common dermatome involve in herpes zoster or shingles

Thoracic dermatome

28

VZIG

Live attenuated

29

Most common target of EBV

B lymphocytes

30

Infectious mononucleosis
Ballerina like lymphocytes or downey cells

EBV

31

Largest herpes virus
Mononucleosis like syndrome
Owl's eye

CMV

32

Most common cardiac abn assoc with CMV

VSD

33

Kaposi sarcoma associated herpes virus (KSHV)

HHV 8

34

6th dse

Roseola infantum - fever without rash, rash without fever. HHV 6

35

Owl's eye inclusions

CMV, Adenovirus

36

"Swimming pool" conjunctivitis

Adenovirus- have fibers protruding frm each penton bases

37

Group specific ag of adenovirus

Hexon

38

Oncogenes of adenovirus

E1A and E1B

39

Polyoma virus that is latent in kidneys

BK virus

40

PML

JC virus

41

Polyoma virus that is animal pathogen

Simian 40 virus

42

Star shape capsomere
#1 cause of cervical CA

Papilloma

43

Papilloma virus transmitted thru sexual contact

An infection with highest oncogenic potential

Condyloma acuminata

44

HPV serotype with highest oncogenic potential

HPV 16 & 18

45

Growing cell of parvovirus

B19

46

Target of B19

Erythroid progenitor cells

47

5th dse

Erythema infectiosum

- generalized erythematous rash that is most prominent in the face (slapped cheek)

48

Symptomatic stage in erythema infectiosum

Immunologic stage