Virus, HPV, norovirus, Antivirus, vaccines (complete) Flashcards Preview

DMD 5245 > Virus, HPV, norovirus, Antivirus, vaccines (complete) > Flashcards

Flashcards in Virus, HPV, norovirus, Antivirus, vaccines (complete) Deck (34):
1

What is the virus family that HIV belongs to

Retroviridae

2

What is the classification of HIV

RNA
icosahedral
enveloped
Single stranded (2 copies)
Positive

3

What is different about the retroviridae (HIV) replication process

it undergoes reverse transcription RdDp (RNA dependent, DNA polymerase) where the RNA is read and turned to DNA, and that viral DNA is inserted into the Cells genome

4

What is the average incubation period for HIV

8-10 years

5

What are the 3 main diseases caused by HIV

1. seroconversion illness (Mono like)
2. AIDS related complex (persistent generalized lymphadenopathy)
3. AIDS

6

What is the main thing that kills someone with HIV AIDS

opportunistic infections

7

What is the most frequent opportunistic tumor of AIDS

Kaposi's sarcoma (malignant lymphomas)

8

What is the most frequent neurological disorder in AIDS

encephalopathy

9

What are the three most common ways HIV Is transmitted

1. Sexual transmission
2. Blood/blood products
3. Vertical Transmission

10

How is HIV diagnosed

screening and confirmation assays

11

what are the two tests performed after someone has been diagnosed with HIV to give them a prognosis

HIV viral load
HIV antigen test

12

What is now used to treat HIV

HAART - highly active anti-retroviral treatment

13

What are the individual drug components of HAART

2 nucleoside reverse transcriptase inhibitors and a protease inhibitor (AZT, Lamivudine, and indinavir)

14

what is the probability of HIV infection from saliva

very low, saliva has a good Anti-HIV activity

15

What is the classification of papillomaviridae (HPV)

DNA
Icosahedral
naked
Double Stranded (circular)

16

What virus is a risk factor for oral, and oropharyngeal cancer

HPV

17

How is HPV transmitted

Sexual Activity, including oral sex
hand shaking
Environmental fomites (showers, door knobs)

18

Is there a vaccine for HPV

yes

19

What family does the norovirus belong to

calciviridae

20

What is the classification of the norovirus

RNA
icosahedral
naked
Single stranded positive

21

what is special about the durability of the calciviridae

they are resistant to heat, and stomach acid

22

What is the most common pathology associated with calciviridae

gastroenteritis

23

does the norovirus affect children or adults more

adults

24

how do we get the norovirus

consumption of shellfish or other contaminated foods
aerosol spread as well as fecal oral

25

what does the norovirus cause

gastroenteritis

26

what is the nickname for the norovirus

winter vomiting disease

27

about what percent of known causes of foodborne illness in the US is caused by the norovirus

50%

28

Where are the majority of the norovirus outbreaks found

long-term care facilities

29

do noroviruses survive in the environment well

yes

30

What is the recommended way to clean up a norovirus infected area or surface

chlorine bleach with a concentration of 1000-5000 parts per million

31

how contagious is the norovirus

very (only 18 viral particles needed)

32

who are carriers for the norovirus

humans are the only known carrier

33

What are the steps in the evolution of viral vaccines

made in animals, then eggs, then cell culture, then recombinant DNA, then peptide

34

how quickly can a vaccine go from the outbreak, to ditribution to the public

months 6-9 or so