WAGR Flashcards
1
Q
What is the genetic defect?
A
Deletion of one copy of chromosome 11p13
WT1 gene = wilms
PAX6 gene = aniridia
2
Q
What are the clinical manifestations of WAGR?
A
W = Wilms tumor (60%) A = Aniridia G = GU anomalies R = mental Retardation
