We - Brain networks and cognition in MS Flashcards
Why do the ventricles of the brain enlarge in MS?
Due to atrophy
Are demyelination and white matter lesions the reason for cognitive problems in MS?
No
What is the reason (partially) for cognitive problems in MS? (2)
Decline in Cortical and deep grey matter volume
What does MEG measure?
Power and Peak frequency of brainwaves.
What does the power of brainwaves mean in MEG processing?
How much activity there is in each frequency band (delta, theta etc.)
What does the peak frequency mean in MEG processing?
Which frequency band has the most activity
With cognitively impaired MS patients, there’s a (lower/higher) peak frequency. This means that there’s a (slow/speed up) of neuronal activity.
Lower, slowing
Cognitively impaired patients have (less/more) gamma power than healthy controls.
Less
Cognitively impaired patients have (lower/higher) alpha1 power than healthy controls.
Higher
MS patients have a (increase/decrease) in low frequency oscillations and a (increase/decrease) in high frequency oscillations.
Increase, decrease
What does integration mean in network brain organization?
Further apart brain regions work together.
What does segregation mean in network brain organization?
Cluster of brain regions located closely together that work together.
What is centrality mean in network brain organization?
The importance of a node in the network
Why is there less integration in MS?
Due to a longer path length.
