Flashcards in Week 2 Deck (30):
What stimulates secretion of ADH?
What inhibits ADH secretion?
Symptoms of diabetes insipidus?
Large volume of dilute urine, constant thirst
Treatment of diabetes insipidus?
How is amount of Na reabsorption regulated?
What is aldosterone secreted in response to?
Rising K or falling Na
Where is most of K reabsopred?
In the proximal tubule
In the absence of aldosterone where is K reabsorped?
What effect does aldosterone have in K?
Where is renin released from?
Granular cells in the JGA
3 causes of renin release?
Reduced pressure in afferent arteriole
Reduces NaCl in DT
Increased sympathetic activity of granular cells
Where is ANP produced?
In the heart
What is the average pH of blood?
What is compensation?
Restoration of pH irrespective of what happens to [HCOs} and PCO2
What is correction?
Restoration of pH [HCO3] and PCO2 to normal
What is respiratory acidosis?
Retention of CO2
3 Causes of respiratory acidosis?
Chronic bronchitis, chronic emphysema, airway restriction
What indicates uncompensated respiratory acidosis?
What occurs in compensation of respiratory acidosis?
H secretion stimulated
All filtered HCO3 is reabsorbed
What is respiratory alkalosis?
Excessive removal of CO2 by the body
3 Causes of respiratory alkalosis?
Low inspired PO2 at altitude
What indicates uncompensated respiratory alkalosis?
pH >7.45 and PCO2 <35mmHg
What is metabolic acidosis?
Excess H from any source other than CO2
3 causes of metabolic acidosis?
Ingestion of acids
Excessive metabolic production of H
Excessive loss of base from the body
What indicates uncompensated Metabolic acidosis?
pH <7.35 and [HCO3] is low
What occurs in compensation of metabolic acidosis?
Ventilation increases and more Co2 is blown off
What is metabolic alkalosis?
Excessive loss of H from the body
3 Causes of metabolic alkalosis?
Loss of HCL from stomach (vomiting)
Ingestion of alkali
What indicted uncompensated metabolic alkalosis?
pH 7.45 [HCO3] is high