Week 2: Factors Affecting Wound Healing (Ch 3) Flashcards Preview

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Flashcards in Week 2: Factors Affecting Wound Healing (Ch 3) Deck (30):
1

What is an acute wound?

a wound induced by surgery or trauma in an otherwise healthy individual (progresses through normal phases of wound healing in predictable time and manner)

2

What is a chronic wound?

a wound whose progression through healing phases if prolonged or arrested due to underlying conditions

3

What does "recalcitrant" mean?

not obedient or not compliant

4

What are deterrents to expedient wound healing?

1. wound characteristics
2. local factors
3. systemic factors
4. inappropriate wound management

5

What are characteristics that affect rate of wound management?

MOI, time since onset, wound location, wound dimensions, temperature, wound hydration, necrotic tissue or foreign bodies, infection

6

What is the ideal wound healing temperature?

37-38 C, 98.6-100.4 F (foam is best)

7

What is the clinical word for a dry wound?

dessication

8

What is the ideal amount of wound hydration?

moist (too dry impedes current, too wet causes maceration)

9

What do foreign bodies do?

prolong inflammation

10

What does necrotic tissue do?

promotes infection

11

what is a normal level of microflora for cultures?
What is concerning

10^3 microbes per g/tissue
>10^5 = infection

12

What are the signs and symptoms of infection?

similar to inflammation, but disproportionate to the wound

13

What are the key differences for chronic wound healing?

senescent cells, increased number of inflammatory mediators, reduced number of tissue inhibitors of MMPs, reduced or arrested epithelialization, greater bioburden

14

What are some local factors that affect wound healing?

circulation, sensation, mechanical stress

15

What are some systemic factors that affect wound healing?

age, nutrition, comorbidities, medication, behavioral risk taking (alcohol, smoking)

16

Tissue perfusion occurs at what level?

microcirculation

17

What is sympathetic response?

vasoconstriction

18

Older adults have a _______ immune response.

Slowed

19

Older adults have a _______ collagen synthesis and strength.

decreased

20

Older adults have epidermal and dermal _______.

atrophy

21

Older adults have a _______ number of sweat and oil glands.

decreased

22

Older adults have a _______ pain perception.

decreased

23

Older adults have a _______ inflammatory response.

decreased

24

Older adults have a _______ number of comorbidities.

greater

25

Older adults have a _______ susceptibility of infection.

increased

26

What happens to individuals with inadequate nutrition?

increased incidence of complications, delayed healing time

27

Which medications mainly affect wound healing?

steroids at doses of >30-40 mg/day, chemotherapy, and NSAIDs

28

How does alcohol abuse affect wound healing?

malnutrition, greater risk for injury, less likely to obtain medical assistance

29

How does smoking affect wound healing?

decreases tissue perfusion, reduces oxygenation, delays normal cellular response

30

Smoking has a _____x increased graft/flap or necrosis risk, and ______x increased infection rate

3, 3-5