Week 3: Congestion (Bolded/Underlined Terms) Flashcards Preview

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Flashcards in Week 3: Congestion (Bolded/Underlined Terms) Deck (41):
1

The MOA for decongestants are _____.

adrenergic agonists (sympathomimetic)

2

The MOA of decongestants are adrenergic agonists which:

A. stimulates _____ in the nasal blood vessels.

B. contracts _____.

C. constricts _____.

D. reduces _____ of the nasal membrane and mucous production

E. facilitates ____.

A. alpha-adrenergic receptors

B. nasal smooth muscles

C. nasal blood vessels

D. inflammation

E. breathing

3

The topical nasal decongestant Ephedrine is ____.

short acting (q4-6 hrs)

4

The topical nasal decongestant Epinephrine is ____.

short acting (q4-6 hrs)

5

The topical nasal decongestant Naphazoline is ____.

short acting (q4-6 hrs)

6

The topical nasal decongestant form of Phenylephrine is _____.

short acting (q4-6 hrs)

7

The topical nasal decongestant Tetrahydrazoline is ____.

short acting (q4-6 hrs)

8

The topical nasal decongestant Xylometazoline is _____.

intermediate acting (q8-10 hrs)

9

The topical nasal decongestant Oxymetazoline is ____.

long acting (q~12 hrs)

10

The topical nasal decongestant Neo-Synephrine is also known as ____.

Phenylephrine

11

The topical nasal decongestant Neo-Synephrine 12 hrs is also known as ____.

Oxymetazoline

12

The topical nasal decongestant Afrin is also known as ____.

Oxymetazoline

13

_____ is an adverse effect of taking topical nasal decongestants. It is temporary discomfort including burning, stinging, sneezing, and increase in nasal discharge.

Rhinitis medicametosa (rebound congestion)

14

One should limit topical nasal decongestant use to ____ due to the adverse effect of rebound congestion.

no more than 3 days

15

______ are alternative options to nasal decongestants and may be used for the treatment of rebound congestion.

They rehydrate the nasal mucosa and liquefy dry secretions for easier removal of dry nasal crusting during dry seasons

Hypotonic Sodium Chloride solutions:

- Ocean
- AYR
- NeilMed Sinus Rinse

16

_____ are the drug of choice (DOC) for pregnant women with nasal congestion.

Hypotonic Sodium Chloride solutions:

- Ocean
- AYR
- NeilMed Sinus Rinse

17

Systemic decongestants have a _____ than topical products because they last longer in our body.

slower onset

18

Sudafed PE is the systemic decongestant form of Phenylephrine with a daily max of ____ for ages 12 years and older.

60 mg

19

Pseudoephedrine (Sudafed, Nexafed, Zephrex-D, Claritin D, Drixoral, Alavert D) is a systemic decongestant with a daily max of _____ for ages 12 years and older.

240 mg

20

Phenylephrine (Sudafed PE) is a systemic decongestant that is available _____.

OTC

21

Pseudoephedrine (Sudafed, Nexafed, Zephrex-D, Claritin D, Drixoral, Alavert D) is a systemic decongestant that is available ____.

behind the counter and dispensed by pharmacists

22

_____ is a systemic decongestant that is available OTC and has a daily max of 60mg.

Phenylephrine (Sudafed PE)

23

_____ is a systemic decongestant that is available behind the counter and has a daily max of 240 mg.

Pseudoephedrine
- Sudafed
- Nexafed
- Zephrex-D
- Claritin D
- Drixoral
- Alavert D

24

You must be 18 years old with a valid ID to purchase ____.

pseudoephedrine

25

The systemic decongestant, pseudoephedrine, contains a purchase limit of ______ /month OR _____ /day PER patient.

9 grams

3.6 grams

26

Traditional formations of systemic decongestants such as ___ and ____ are NOT meth-resistant pseudoephrine and would produce a yield of 505 mg of methamphetamine per box of pseudo ephedrine.

Sudafed (Pseudoephedrine)

Claritin-D (Pseudoephedrine + Loratadine)

27

New formations of systemic decongestants such as ___ and ____ are meth-resistant pseudoephrine and would produce a yield of 0 mg of methamphetamine per box of pseudo ephedrine.

Nexafed
Zephrex-D

28

The Drug-Drug interactions (DDI) with systemic decongestants such as MAO or COMT inhibitors can cause _____,

increase in blood pressure

29

MAO inhibitors are a drug-drug interaction with systemic decongestants and can cause increase in blood pressure. Do NOT take systemic decongestants for at least _____ after the MAOIs are discontinued.

14 days

30

Systemic decongestants are _____ for women who are pregnant and lactating.

category C

- only use if the benefit outweighs risk to the fetus
- use alternative agents if possible (like Ocean Spray or Afrin)

31

Systemic decongestants may decrease _____ and ____.

- breast milk production
- fetal blood flow

32

For patient counseling on systemic decongestants, tell the patient to AVOID taking ____

right before sleep because it has a stimulant effect.

instead, take it 2-3 hours prior to sleep

33

For patient counseling on systemic decongestants, caution patients with ____.

hypertension (HTN) because it may increase heart rate

34

For patient counseling on systemic decongestants, tell the patient to stop use and ask a doctor if _____.

symptoms did not improve after 7 days.

35

REVIEW:
_____ may cause rebound congestion.

topical nasal decongestants

(systemic nasal decongestants DO not cause rebound congestion)

36

REVIEW:
Stop use of Nasal decongestants after ____.

Stop use of Systemic decongestants after ____.

nasal: 3 days

systemic: 7 days

37

REVIEW:
The onset of Nasal decongestants are ____.

The onset of Systemic decongestants are ____.

nasal: fast

systemic: slow

38

REVIEW:
Is there DDI with MAOIs when taking Nasal decongestants?

NO

39

REVIEW:
Is there DDI with MAOIs when taking Systemic decongestants?

YES

40

Are Nasal decongestants kept behind the counter?

NO

41

Are Systemic decongestants kept behind the counter?

Phenylephrine: NO

Pseudoephedrine: YES