week 4 Flashcards Preview

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Flashcards in week 4 Deck (16):
1

clotrimazole spectrum

broad

2

application of clotrimethazole

topical

3

clotrimethazole inhibits

14a yeast demethylase

4

what cant happen when clotrimethazole is administered

the fungi can no longer convert lanosterol to ergosterol

5

name a cytochrome p450 enzyme

yeast 14a bemethylase

6

fluconazole is administered

orally

7

fluconazole is against

vaginal candidiasis

8

nysatin binds to

ergosterol

9

amphoteracin binds to

ergosterol

10

pyrimethamine is used against

p.falcifarum malaria and toxoplasmosis

11

what does pyrimethamine inhibit

dihydrolate reductase

12

what cant the parasite make with pyrimethamine

purine and pyramidine

13

what is pyrimethamine highly selective against

gondii

14

quinine MOA

stops the parasite destruction of haem

15

quinine is also a

blood schizonticide
gameticide to vivax and malariea

16

atremether

interupts the parasites haem food vacuole, creates oxygen and carbon free radicals