Week One - An Intro To Infection

Question 1

How to micro-organisms cause disease - 5 stages

Answer 1

Exposure - adherence - invasion - multiplication - dissemination

Question 2

What is virulence? What are virulence factors?

Answer 2

Virulence is the degree of pathogenicity within a species - it’s ability to cause disease. Factors include ends and exotoxins. They achieve the following: colonisation, immunoevasion, entry and exit of cell or obtaining nutrition.

Question 3

What are the disease determinants?

Answer 3

Pathogen - virulence factors, inoculum size (how much you are exposed to), anti microbial resistance
Patient - site of infection, co-morbidities

Question 4

Name three other environmental factors that allow people to get infections, eg water. Give an example for each.

Answer 4

Water - botulism, cholera
Food - salmonella, e.coli, listeria
Air- influenza, measles, small pox
Surfaces - c.diff, MRSA