Derm > Wk 6 Antineoplastics > Flashcards

Wk 6 Antineoplastics Flashcards

(7 cards)

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0
Q

Fludarabine

A

purine analog
no DNA synthesis
S-phase specific

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1
Q

Methotrexate

A

inhibits folate synthesis
inhibits DNA synthesis
S-phase specific

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2
Q

Cyclophosphamide

A

alkylating agent
DNA damage
not phase specific

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3
Q

Cisplatin

A

PLATnum crosslinks DNA

cell cycle nonspecific

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4
Q

Doxorubicin

A

intercollates DNA

cell cycle nonspecific

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5
Q

Etoposide

A

topo II inhibitor

G2/S inhibitor

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6
Q

Paclitaxel

A

spindle stabilizer

M phase specific

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