Y5 - Chemotherapy, hormone therapy & biological agents Flashcards Preview

Year 5 Cancer > Y5 - Chemotherapy, hormone therapy & biological agents > Flashcards

Flashcards in Y5 - Chemotherapy, hormone therapy & biological agents Deck (12):
1

def

a type of cancer treatment which uses anti-cancer drugs

2

when may chemotherapy be used

with the intent of curing the patient
or to prolong life

3

what sort of therapy is chemotherapy

a systemic therapy

4

who is HRT used for

menopausal women

5

who is ART used for

males with low testosterone

6

indications

cancer, rheumatoid arthritis, SLE, MS

7

complications

myelosuppression (causing immunosuppression), mucositis, alopecia

8

different types of chemotherapeutic agents

akylating agents
antimetabolites
antimicrotubule agents
topoisomerase inhibitors
cytotoxic antibiotics

9

how do akylating agents work

akylate RNA and DNA
if DNA tries to replicate, or repair akylation, DNA strands break and apoptosis occurs

10

how do antimetabolites work

impede DNA and RNA synthesis
block enzymes required for DNA synthesis

11

how do anti-microtubule agents work

block cell division by preventing microtubule function

12

how do topoisomerase inhhibitors work

interferes with DNA unwinding