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year 3 passssmeddd Flashcards

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1
Q

how do you give prophylaxis for tumour lysis syndrome

A

IV allopurinol or Iv rasburicase

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2
Q

what is found in cryoprecipitate

A

factor VIII, fibrinogen, von Willebrand factor and factor XIII

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3
Q

what type of anaemia does methotrexate therapy cause

A

can cause folate deficiency so therefore can cause
-megaloblastic macrocytic anaemia

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4
Q

which Hodgkin’s lymphoma carries the best prognosis

A

lymphocyte predominant

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5
Q

philadelphia chromosome, t(9:22)

A

CHRONIC MYELOID LEUKAEMIA

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6
Q

which anticoagulant for DVT

A

DOAC!!!!!!!!!!!!!!!
-apixaban or rivaroxaban

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7
Q

isolated rise in gamma GT in the context of macrocytic anaemia suggests that what is the cause?

A

alcohol excess

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8
Q

which is the most common type of haemophilia

A

A!!!!! !!! !
factor 8 deficiency

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9
Q

cancer patients with a VTE, what treatment

A

DOAC for 6 months

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10
Q

DVT investigation: if the scan is negative, but the D-dimer is positive?

A

stop anticoagulation and repeat scan in 1 week

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11
Q

where are vestibular schwannomas usually found

A

the cerebellopontine angle

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12
Q

at what level of the spinal cord does autonomic dysreflexia occur

A

above T6

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13
Q

can you give someone with poorly controlled epilepsy sertraline

A

no

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14
Q

second line treatment for OCD if SSRI contraindicated

A

clomipramine

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15
Q

how does controlled hyperventilation work to reduce ICP

A

reduces CO2 > vasoconstriction of cerebral arteries > reduced ICP

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16
Q

is the forehead spared in bell’s palsy

A

NOOOOO
-cannot raise eyebrows
-LMN lesion

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17
Q

triple test results for downs syndrome

A

increased HCG
decreased PAPP-A
thickened nuchal translucency

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18
Q

investigation for suspected miscarriage

A

TVUSS

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19
Q

when can medical management be used for an ectopic

A

1) An unruptured embryo
2) <35mm in size
3) Have no heartbeat
4) Be asymptomatic
5) Have a B-hCG level of <1,000IU/L and declining

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20
Q

can an SSRI be taken with warfarin

A

no
-increases risk of bleeding especially in elderly people

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21
Q

what is richter transformation

A

when CLL transforms into aggressive high grade B cell lymphoma

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22
Q

what does parovirus B19 infection cause

A

slapped cheek (aka erythema infectiosum)
-this can cause aplastic crisis in sickle cell

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23
Q

A swab reveals the presence of ballooned multinucleated giant cells and eosinophilic inclusion bodies.

Study These Flashcards
A

herpes simplex 2

24
Q

when should warfarin be stopped and vitamin K administered

Study These Flashcards
A

when the INR is over 8

25
what medication for chemo induced nausea
odanestron
26
which neurofibromatosis causes peripheral neurofibromas and axillary/groin freckles
1
27
what nerve injury are mid humeral shaft fractures associated with
radial nerve
28
what should you think when there is a mixture of LMN and UMN signs
MND
29
what is the most common cause of brain mets
LUNG CANCER
30
what is subdural haemorrhage caused by
damage to bridging veins between cortex and venous sinuses
31
which contraception has the highest success rate
progesterone only implant
32
if you miss one POP how long do you need to use barrier methods for
48 hours
33
lynch syndrome increases ur risk of which repro cancer the most
endometrial the most -then ovarian
34
how do you assess fetal growth in obese women
USS
35
if a woman who is pregnant has a BMI of 50 what do they need further encouragement to do
breastfeed -obese women are less likely to breast feed
36
which part of the MMR can cause obstructive infertility and reduce spermatogenesis
mumps
37
when can pregnant women get a cervical smear
not until they are 3 months post partum
38
how does a pituitary tumour decrease fertility in males
-decrease LH, FSH -decreased testosterone
39
how do hypothalamus disorders decrease fertility in males
-decrease LH, FSH -decreased testosterone
40
how does hyperthyroidism decrease fertility in males
decreased sexual function
41
how does hypothyroidism decrease fertility in males
increased prolactin
42
how does diabetes decrease fertility in males
decreased testosterone decreased sexual function
43
investigation for primary ovarian insufficiency (premature ovarian failure)
FSH levels x2
44
what is gravida
the number of times a woman has been pregnant regardless of the gestation at delivery and includes current pregnancy
45
what does parity mean
the number of potentially viable babies a woman has delivered; this includes all live births and still births delivered after 24 weeks. So, this is written as P2 and is followed by “+” which represents all the pregnancies up to 24 weeks that did not result in live births (delivered 2 babies)
46
which HRT increases risk of VTE
oral oestrogen only
47
which HRT for someone with high risk of DVT
transdermal oestrogen patch -also need to insert mirena IUS for the progesterone part
48
which gynaecological malignancy is associated with gelatinous tumour in the peritoneal cavity
ovarian
49
coffee bean nuclei and exner bodies
sex cord ovarian tumour
50
where can the fundus be felt at 12 weeks
symphysis pubis
51
active labour over how many hours puts u at risk of PPH
12
52
which movement before expulsion
external rotation
53
What antibodies are formed by the mother when first exposed to a red cell antigen?
IgM
54
first line investigation for urinary incontinence
urine dipstick
55
what is the nerve supply to the urethral smooth muscle
Sympathetic nerves derived from the spinal cord at T10 to L2, but descending to the bladder and urethra via the hypogastric nerves
56
can pyroxidine be used for hyperemesis gravidarum
no
57
name 4 things that causes a raise in CA125 levels
-endometriosis -ovarian cancer -pregnancy -pancreatitis

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