Zofran (Ondansetron)

Question 0

Action

Answer 0

Blocks serotonin at 5-HT3 receptor sites in Vagal nerve terminals

Question 1

Class (2)

Answer 1

• Antiemetic

- Serotonin type 3 (5-HT3) agonist

Question 2

Indication

Answer 2

Prevent nausea and vomiting

Question 3

Dose/Route

Answer 3

• 4 mg IV (repeat if no effect in 5 min)
• Onset: rapid
• Peak: 15-30 min
• Duration: 4-8 hr

Question 4

Peds Dose

Answer 4

0.1 mg/kg IV

Question 5

Standard Prep

Answer 5

4 mg/2 ml

Question 6

Contraindication

Answer 6

Hypersensitivity

Question 7

Side Effects (8)

Answer 7

• Hypotension
• Bradycardia
• Blurred vision
• Bronchospasm
• Urinary retention
• Constipation/diarrhea
• Anxiety
• Dizziness

Question 8

Precaution

Answer 8

Use in caution in people with hepatic insufficiency