1 Flashcards

1
Q

3 unifocal/multifocal lesions

A

abscess, granuloma, neoplasia

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2
Q

PAS

A

1

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3
Q

GMS

A

1

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4
Q

Ziehl Neelsen

A

1

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5
Q

Prussion blue

A

1

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6
Q

Masson trichrome

A

1

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7
Q

Congo red

A

1

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8
Q

Oil Red O

A

1

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9
Q

Neoplasia

A

1

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10
Q

infarction

A

localized area of necrosis

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11
Q

hydropic change

A

swelling

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12
Q

endogenous generation of ROS

A

atp synthesis, rxn with transition metals, no, leukocytes

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13
Q

pyknosis

A

clumping, condensation and shrinkage of nuclear chromatin. then karyorrhexis then karyolysis

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14
Q

in what necrosis what access form??

A

liquefactive

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15
Q

steatosis

A

fatty change

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16
Q

what are the two endogenous heme derived pigment

A

hemosiderin and bilirubin

17
Q

heart failure cells

A

term applied to pulmonary macrophages that accumulate

hemosiderin secondary to left-sided heart failure; this is briefly explained

18
Q

“bronze diabetes”

A

increased melanin production

19
Q

kernicterus

A

unconjugated bilirubin in newborns

20
Q

lipfuscin

A

endogenous pigments non heme derived

21
Q

anthracosis

A

blackened lymph nodes from exogenous pigments

22
Q

amyloid

A

A pathological, fibrillary, proteinaceous substance deposited in the interstitium of several
organs where it may lead to organ dysfunction; condition is known as amyloidosis
Beta amyloid associated with alzheimer

23
Q

metastatic calcification

A

increased blood calcium. opposite is dystrophic

24
Q

what is always required for granulomatous inflammation?

A

epitheloid cells

25
Q

granulation tissue

A

needed for repair of tissue. NOT granulomas

26
Q

what cells are seen in association with granulomas?

A

giant cells

27
Q

chediak higashi syndrome

A

disorders involving PMN granules

28
Q

what cell contains MPO?

A

PMNs, neutrophils

29
Q

what do macrophages rely on?

A

lactoferrin and lysozyme (muramidase)