1 Flashcards
What is Non Specific immunity
First time encounter- immunity that will respond to any antigen
What is Specific immunity
If body detects antigen it’s already met it is trained to remember and deal with that specific antigen
Non- specific mechanisms (PIND)
Phagocytosis, Inflammatory response, Natural antimicrobial substances, Defence at body surface
Specific immunity mechanism
Cells and proteins within blood and lymph Attach, Disarm, Destroy and Remove foreign bodies
Long lasting
The HMC complex controls immune response by distinguishing between ‘self’ and ‘non self’
What is the primary response
When an B cell encounters an antigen for the first time it produces memory and plasma cells
What is the Secondary response
On the second encounter- it is quicker as the memory cells stick to and destroy antigens straight away
How do antibodies protect the body? (3)
Helping other immune cells digest antigens
Inactivating toxic substances released by bacteria
Attacking bacteria and viruses directly
What does IgA do?
Help defend against microorganisms that enter through mucous membranes.
Where is IgA found?
Bloodstream, breast milk, tears.
What does IgD do?
It activates B lymphocytes, basophils and mast cells. The function is not well understood.
What does IgE do?
Trigger immediate allergic reactions. It binds to Basophils in the Blood stream and to MasT cells in Tissue.
What does IgE release?
Histamine upon encountering an allergy- resulting in inflammation of that area.
When is IgG released?
It is released when there is an antigen that has already been encountered. It is the secondary immune response as it is faster and produces more antibodies than primary.
Where is IgG found?
In bloodstream and only one that goes across placenta- so the foetus can produce own antibodies.
When is IgM released?
In the primary response
