1- Synaptic Transmission

Question 1

Types of synaptic transmission?

Answer 1

1- (Direct) Electrical transmission

2- (Indirect) Chemical transmission

Question 2

A single presynaptic neuron can give?

Answer 2

2000 synaptic

Question 3

A single post synaptic neuron can receive up to?

Answer 3

200000 pre synaptic terminals

Question 4

This type is the most common synapses?

Answer 4

Axodendritic

Question 5

The axodendritic represents up to?

Answer 5

80-98% of all synapses

Question 6

This is the most excitable ?

Answer 6

Axoaxonic

Question 7

Represent from 2-20 % of all synapses?

Answer 7

Axosomatic

Question 8

Least common and least numerous and most excitable synapses?

Answer 8

Axoaxonic

Question 9

The most common and least excitable synapses?

Answer 9

Axodendritic

Question 10

There are three types of synaptic vesicles?

Answer 10

1- Small clear vesicles
2- Small granular vesicles
3- Large granular vesicles

Question 11

The small clear vesicles contain rapidly acting chemical transmitter like?

Answer 11

1- Acetylcholine
2- Glycine
3- Glutamate
4- GABA

Question 12

The small granular vesicles contain?

Answer 12

Catecholamines (Epinephrine, Norepinephrine, Dopamine)

Question 13

The large granular vesicles contains slowly acting …… ?

Answer 13

Neuropeptide (like Hormones : anti diuretic hormone and oxytocin hormone)

Question 14

Type of SNARE proteins?

Answer 14

1) v-SNARE: on the membrane of synaptic vesicles

2) t-SNARE: on the pre synaptic terminal membrane

Question 15

GABA is?

Answer 15

Ionotropic receptor

Question 16

Serotonin is?

Answer 16

Metabotropic Receptor

Question 17

Which of the following are the most numerous ?

Answer 17

Axodendritic

Question 18

Which of the following is the most excitable ?

Answer 18

Axoaxonic

Question 19

Which of the following is the least numerous ?

Answer 19

Axoaxonic

Question 20

Which of the following is the least excitable ?

Answer 20

Axodendritic

Question 21

Which of the following is the second numerous ?

Answer 21

Axosomatic

Question 22

Which of the following is the second excitable?

Answer 22

Axosomatic

Question 23

Which of the following releases from small clear vesicles?

Answer 23

ACh (Acetylcholine)

Question 24

Which of the following releases from small granular vesicles?

Answer 24

Norepinephrine

Question 25

Which of the following releases from large granular vesicles?

Answer 25

Neuropeptide

Question 26

v-SNARE protein present in the?

Answer 26

Vesicular membrane

Question 27

t-SNARE protein present in ?

Answer 27

Pre synaptic terminal membrane

Question 28

Which of the following is a mechanism in removal of Neurotransmitters from the Synaptic Cleft?

Answer 28

Removal by glial cells

Question 29

EPSP reaches its peaks after

Answer 29

11 - 11.5 msec

Question 30

Temporal summation originating from ?

Answer 30

One presynaptic neuron

Question 31

Spatial summation originating from

Answer 31

multiple presynaptic neurons

Question 32

If we have 30 excitatory neurons and 10 inhibitory neurons

Answer 32

membrane facilitated

Question 33

If we have 50 excitatory neurons and 10 inhibitory neurons

Answer 33

Action potential happen

Question 34

If we have 10 excitatory neurons and 20 inhibitory neurons

Answer 34

membrane hyperpolarized

Question 35

What is the neurotransmitter release in presynaptic inhibition?

Answer 35

GABA

Question 36

What is the neurotransmitter release in presynaptic facilitation?

Answer 36

Serotonin

Question 37

What is the mechanism of action of mirtazapine?

Answer 37

• Anti depressant

inhibition of alpha 2 receptor + Increase the synaptic release of norepinephrine and serotonin

Question 38

What is the mechanism of action of mirtazapine?

Answer 38

increase the synaptic release of norepinephrine and serotonin