Lect 7. The Ovarian Cycle, Ovulation, and Uterine Changes Flashcards
Ovulation is linked to uterine changes during (1)___
menstrual cycle
Ovulation is linked to uterine changes during menstrual cycle
→ changes driven by ____ (2 types of hormones and their origin)
follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from pituitary gland
Ovulation
The role of follicle-stimulating hormone (FSH)
stimulates development of primary follicles into secondary follicles
Ovulation
follicle-stimulating hormone (FSH) stimulates development of primary follicles into secondary follicles
→ granulosa cells respond to FSH by ____
producing estrogens
Ovulation
follicle-stimulating hormone (FSH) stimulates development of primary follicles into secondary follicles
→ ___ respond to FSH by producing estrogens
LH
granulosa cells
4 Causes of LH surge from the pituitary glands
- Oocyte to complete first phase of meiosis, creates secondary oocyte and first polar body
- Secondary oocyte initiates second phase of meiosis but arrests in metaphase; will not complete meiosis unless it is fertilized
- Stimulates granulosa cells to create progesterone
- Graafian follicle ruptures, allowing ovulation
4 Causes of LH surge from the pituitary glands
- Oocyte to complete first phase of meiosis, creates ____
- Secondary oocyte initiates second phase of meiosis but arrests in ___; will not complete meiosis unless it is ___
- Stimulates granulosa cells to create ___
- Graafian follicle ruptures, allowing ___
- secondary oocyte and first polar body
- metaphase; fertilized
- progesterone
- ovulation
4 Causes of LH surge from the pituitary glands
- Oocyte to complete ___, creates secondary oocyte and first polar body
- Secondary oocyte initiates ___ but arrests in metaphase; will not complete meiosis unless it is fertilized
- Stimulates ___ to create progesterone
- ___ ruptures, allowing ovulation
- first phase of meiosis
- second phase of meiosis
- granulosa cells
- Graafian follicle
Ovulation
The cumulus oophorus travel with it and arrange themselves into new structure called ____
corona radiata
Ovulation
The role of corona radiata
surrounding zona pellucida and oocyte
Ovulation
____ travel with it and arrange themselves into new structure, corona radiata, surrounding zona pellucida and oocyte
The cumulus oophorus
Ovulation
Granulosa cells remaining in ovary form a structure called ____, producing progesterone
corpus luteum
Ovulation
Granulosa cells remaining in ovary form a structure called corpus luteum, producing ___
progesterone
Ovulation
____ remaining in ovary form a structure called corpus luteum, producing progesterone
Granulosa cells
Ovulation
If fertilization does not occur, corpus luteum dwindles to become (1)___ and (2)___ drop precipitously
- corpus albicans
- levels of progesterone
Hormonal changes of menstrual cycle also affect the lining of the uterus
→ Is it possible?
Yes
Uterine Changes
As levels of FSH climb, granulosa cells produce (1)____(estrone and 17 β-estradiol) that induce growth of endometrium into its (2)____
- estrogens
- proliferative phase
Uterine Changes
As levels of ___ climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
FSH
As levels of FSH climb, ____ produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
granulosa cell
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol)
→ The role of estrogen to uterine changes
induce growth of endometrium into its proliferative phase
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
→ spiral arteries and glands in (1)____ of endometrium grow as endometrium becomes thicker, developing (2)____
- basal layer
- follicular layer
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
→ (1) ____ in basal layer of endometrium grow as (2)____ becomes thicker, developing follicular layer
- spiral arteries and glands
- endometrium
As levels of FSH climb, granulosa cells produce estrogens (estrone and 17 β-estradiol) that induce growth of endometrium into its proliferative phase
-> Identify
Uterine Changes
Under the influence of ____, progesterone (and estrogens) from corpus luteum and promote further growth of endometrium into progestational phase, making it ready to host the fertilized oocyte
LH
Uterine Changes
Under the influence of LH,
→ rolesof progesterone (and estrogens) from corpus luteum ?
They promote further growth of endometrium into progestational phase, making it ready to host the fertilized oocyte
Uterine Changes
Under the influence of LH,
→ progesterone (and estrogens) from corpus luteum and promote further growth of endometrium into (1)____, making it ready to host the (2)____
progestational phase
fertilized oocyte
Uterine Changes
If fertilization not occur, (1)___ drop and (2)____ close
- levels of progesterone from corpus luteum
- spiral arteries to follicular layer of endometrium
Uterine Changes
If fertilization not occur, levels of progesterone from corpus luteum drop and spiral arteries to follicular layer of endometrium close
→ What happen to follicular layer?
follicular layer becomes ischemic, dies, and is shed during menstrual phase
