4 transport across cell membranes Flashcards

1
Q

what is the cell surface membrane made up of?

A

phospholipids

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2
Q

explain the fluid mosaic model

A

phospholipids form a bilayer that constantly moves around relative to one another in a fluid structure
protein molecules in bilayer unevenly distributed forming a mosaic

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3
Q

what is the function of the phospholipid bilayer?

A

to allow lipid soluble substances to enter and leave the cell

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4
Q

name what components are within the phospholipid bilayer

A

phospholipids
cholesterol
channel proteins
carrier proteins
receptor proteins
enzymes
glycoproteins
aquaporins

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5
Q

what does the phospholipid bilayer allow through by simple diffusion?

A

lipid soluble molecules (non polar)

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6
Q

what is the function of cholesterol in the phospholipid bilayer?

A

decreases permeability and increases stability

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7
Q

what is the function of a channel protein?

A
  • only allow specific charged ions or small molecules to move across the membrane by facilitated diffusion
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8
Q

what is the function of a carrier protein?

A

help with the transport of ions/ polar molecules/ large molecules by facilitated diffusion and active transport

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9
Q

what could bind to receptor proteins?

A

insulin/hormones

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10
Q

do all cells have the same receptor proteins?

A

no

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11
Q

what is the function of a glycoprotein in a phospholipid bilayer?

A

important in cell recognition often acting as antigens
identify cells as self or non self

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12
Q

where are glycoproteins produced?

A

golgi body

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13
Q

do all cells have glycoproteins on their cell surface membrane?

A

yes

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14
Q

what is an aquaporin?
what can a cell with lots of aquaporins do?

A

special type of channel protein specific to water
a cell with lots of aquaporin can carry out osmosis easily

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15
Q

what can movement of substances into or out of cells occur by?

A

simplediffusion
facilitated diffusion
osmosis
active transport
co transport
exo/endocytosis

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16
Q

does simple diffusion require ATP?

A

no

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17
Q

define diffusion

A

the net movement of molecules from an area or higher concentration to a lower concentration across a partially permeable membrane

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18
Q

give an example of what simple diffusion can help move through the membrane

A

O2
oestrogen

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19
Q

give the equation for ficks law

A

rate of diffusion =
surface area x conc grad/diffusion distance

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20
Q

what factors affect the rate of diffusion?

A

temperature
surface area
conc gradient
diffusion distance

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21
Q

how does temperature affect the rate of diffusion?

A

increased kinetic energy leads to faster rate of diffusion

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22
Q

how does surface area affect the rate of diffusion?

A

larger surface area provides more space for molecules to pass through- faster diffusion

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23
Q

how does concentration gradient affect the rate of diffusion?

A

as concentration difference increases, rate of diffusion increases

24
Q

how does diffusion distance affect the rate of diffusion?

A

the shorter the diffusion distance the faster the molecules will travel through

25
Q

what part of the phospholipid bilayer is hydrophobic and hydrophilic?

A

hydrophobic tails
hydrophilic heads

26
Q

why cant hydrophilic substances pass through the tails of the bilayer?

A

because the fatty acid tails are non polar and repel polar molecules

27
Q

how do water soluble molecules move through the membrane?

A

through channel or carrier proteins via facilitated diffusion

28
Q

does facilitated diffusion require ATP?

A

no

29
Q

define osmosis

A

the net movement of water molecules from higher water potential to a solution lower water potential through a partially permeable membrane

30
Q

what is water potential?

A

the pressure exerted on the membrane due to free moving water molecules colliding with it

31
Q

what is water potential measured in?

A

kPa

32
Q

what solution has the highest water potential?

A

pure water

33
Q

how many kPa does pure water have?

A

0

34
Q

why does water have 0kPa?

A

because all water molecules are free moving

35
Q

what happens when you add a solute to a solution?

A

the water potential becomes more negative

36
Q

why does adding a solute to a solution make it have a more negative water potential?

A

H2o is a dipole so is attracted to charges on solutes, decreasing the amount of free moving water molecules so less pressure exerted onto membrane

37
Q

which way does water move when the inside of a cell has a higher water potential than outside?

A

down water potential gradient/moves to inside the cell

38
Q

which way does water move when the inside of a cell has a lower water potential than outside?

A

down water potential gradient/moves to outside the cell

39
Q

what can happen to an animal cell when there is a higher water potential inside the cell than outside?

A

swelling and lysis

40
Q

what can happen to a plant cell when there is a higher water potential inside the cell than outside?

A

swelling and increased mass
NOT lysis

41
Q

why don’t plant cells undergo lysis if water is moving into the cell b osmosis?

A

cellulose prevents lysis

42
Q

what is lysis?

A

bursting

43
Q

what can happen to an animal cell when there is a higher water potential outside the cell than inside?

A

crenation (shrivelling)

44
Q

what can happen to a plant cell when there is a higher water potential outside the cell than inside?

A

cells plasmolyse (cell membrane pulls away from cell wall)

45
Q

what does isotonic mean?

A

no net movement of water in or out of cells

46
Q

what is active transport?

A

transportation of molecules against a concentration gradient (from low concentration to high concentration)

47
Q

what does active transport use to tranport molecules?

A

ATP
carrier proteins

48
Q

how does active transport use carrier proteins and ATP to transport molecules against a concentration gradient?

A
  1. molecule binds to specifically complementary binding site on carrier protein
  2. ATP hydrolysed into ADP + Pi releasing small amounts of energy/phosphorylating protein
  3. carrier proteins tertiary structure changes, transporting molecule across
49
Q

what are two types of active transport?

A

exo and endocytosis

50
Q

briefly describe the process of exocytosis

A

uses golgi vesicles to move large quantity of molecules to be secreted form inside the cell to outside of the cell

51
Q

briefly describe the process of endocytosis

A

cell surface membrane ‘pulled’ inwards creating a vesicle

52
Q

what do exocytosis and endocytosis require ATP for?

A

movement/creation of vesicles

53
Q

what happens to transport across membranes if aerobic respiration stops?

A

active transport can’t occur due to less ATP being made

54
Q

what happens to transport across membranes if the tertiary structure of a carrier protein changes?

A

active transport and facilitated diffusion inhibited as molecule is no longer specifically complementary

55
Q

describe how amino acids are absorbed from the ileum into the blood

A
  1. Na+ actively transported out of epithelial cell into the blood by NaK pump
  2. creating a conc grad of Na+
  3. Na+ and amino acid enter by facilitated diffusion
  4. Na+ moves into the cell down its conc grad
  5. amino acids move into the cell against their conc grad
  6. amino acids move into the blood by facilitated diffusion