Pituitary Gland Flashcards
1
Q
Microadenoma is less than …….
A
1 cm
2
Q
Describe microscopic features of pituitary adenoma
A
-uniform polygonal cells arranged in sheets, papillary or trabecular patterns with scant stroma
-cytoplasm may be acidophilic, basophilic, chromophobic, nuclei may be uniform or pleomorphic
-supporting CT reticulin is sparse thus it is soft & gelatinous
3
Q
Clinical picture of pituitary adenoma
A
- Mass effect with visual disturbance
- Hypopituitarism due to destruction of ant pituitary by non-functioning adenoma
- Symptoms & signs related to hormone prouction
4
Q
Mention manifestation of ACTH overproduction
A
Cushing’s disease
Hyperpigmentation (MSH)
5
Q
List causes of ant pituitary hypofunction
A
- Non-functioning pituitary adenoma
- Ischemic necrosis of ant pituitary (Sheehan syndrome, postpartum necrosis)
- Ablation of pituitary by surgery or radiation
- Inflammatory lesion as sarcoidosis, trauma & metastasis