Pituitary Gland Flashcards

1
Q

Microadenoma is less than …….

A

1 cm

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2
Q

Describe microscopic features of pituitary adenoma

A

-uniform polygonal cells arranged in sheets, papillary or trabecular patterns with scant stroma
-cytoplasm may be acidophilic, basophilic, chromophobic, nuclei may be uniform or pleomorphic
-supporting CT reticulin is sparse thus it is soft & gelatinous

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3
Q

Clinical picture of pituitary adenoma

A
  1. Mass effect with visual disturbance
  2. Hypopituitarism due to destruction of ant pituitary by non-functioning adenoma
  3. Symptoms & signs related to hormone prouction
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4
Q

Mention manifestation of ACTH overproduction

A

Cushing’s disease
Hyperpigmentation (MSH)

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5
Q

List causes of ant pituitary hypofunction

A
  1. Non-functioning pituitary adenoma
  2. Ischemic necrosis of ant pituitary (Sheehan syndrome, postpartum necrosis)
  3. Ablation of pituitary by surgery or radiation
  4. Inflammatory lesion as sarcoidosis, trauma & metastasis
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