radiology Flashcards
what is an alpha particle composed of?
2 protons and 2 neutrons
how far can an alpha particle travel?
few inches
what is a beta particle composed of?
electron
how far can a beta particle travel ?
few feet
what is the difference between atoms and ions?
atoms have equal numbers of protons and electrons, ions do not
when radiation passes through matter, it ionises atoms and deposits energy locally, what is the approximate quantity of energy?
35eV
what is the most significant effect of ionising radiation ?
DNA damage - can be seen on faulty repair of chromosome breaks
radiation can damage DNA directly and indirectly - describe the direct effect
radiation interacts with atoms of a DNA molecule or other important cell components
radiation can damage DNA directly and indirectly - describe the indirect effect
radiation interacts with water in the cell producing free radicals which can cause damage
what are free radicals?
highly unstable high reactive molecules
which radiation usually is the cause of double strand breaks in DNA?
alpha
the biological effect of radiation will depend on a number of factors, list 4
type of radiation
amount
time over which dose is received
tissue or cell type irradiated
what is the effect of radiation dose on cell repair capacity?
low dose rate - less damaging and cells can repair
high dose rate - DNA repair capacity likely to be overwhelmed
which tissues are at higher risk of cancer following large radiation exposures?
oesophagus
thyroid
breast
tissue radio sensitivity is dependent on two factors which are
the function of the cells making up the tissue
if the cells are actively dividing
which type of cell are very radiosensitive?
stem cells - divide frequently
which cells are less sensitive to radiation?
differentiated as the do not divide
true or false
the more rapidly a cell is dividing, the more radiosensitive
true
give an example of highly radiosensitive tissue
bone marrow
lymphoid tissue
GI
give an example of moderately radiosensitive tissues
skin
lung
lens
which tissues are least radiosensitive
bone and cartilage
connective tissue
CNS
what are the 4 possible outcomes of radiation hitting the cell nucleus?
no change
dna mutation - repaired
dna mutation - cell death
dna mutation - cell survives but is mutated
what is the units of absorbed dose?
Gray Gy
what does absorbed dose measure?
the energy deposited by radiation
what is the equivalent dose?
absorbed dose multiplied by a weighting factor depending on the type of radiation
what are the units for equivalent dose
sieverts Sv
what is the weighting factor for alpha particles?
20
what is the weighting factor for beta gamma and x-rays
1
what is the LNT model (Linear no threshold model) used for ?
to estimate the long term biological damage from radiation
what are the assumptions of the LNT model?
damage is directly proportional to radiation dose
radiation is always harmful with no safety threshold - several small exposures have same effect as one large
what is the risk of cancer from an intra-oral x-ray?
less than 1 in 10,000,000
what is the associated risk of cancer of a dose of 1mSv?
1 in 20,000
how can you reduce damage to CR plates?
insert between two plastic sheets
clean and replace damaged detectors
what are the adult diagnostic reference levels DRLs for intra-oral examinations?
0.9mGy for digital sensore
1.2mGy for phosphor plates and film
what are the current DLRs for child intra oral examinations?
0.6mGy digital sensors and 0.7mGy phosphor plates and film
what are the elements of radiation protection philosophy?
justification
optimisation
dose limitation
what does justification mean in radiology?
must have sufficient benefit to individual or society to offset detriment
how do we optimise radiographs ?
ALARP
individual doses and people exposed should be As Low As Reasonable Practicable
dose optimisation is a legal requirement, how do we ensure dose is optimised?
ALARP
use rectangular collimators
use E speed film
kV range 60-70
focus to skin distance >200mm
circular collimators increase radiation dose by how much?
40%
how far should the controlled area extend from X-ray tube and patient?
1.5m
what are the two types of radiation effects?
deterministic
stochastic
what are deterministic effects of radiation?
tissue reactions
severity of effect is related to dose received
only occur above certain dose
what are stochastic effects of radiation?
probability of occurrence is related to dose received