1.4.2 hydrophobic signals and control of transcription Flashcards
where can hydrophobic signalling molecules diffuse
directly through the phospholipid bilayers of membranes
where do hydrophobic signalling molecules bind
to intracellular receptors
what are receptors for hydrophbic signalling molecules
transcription factors
what are transcription factors
proteins that when bound to DNA can either stimulate or inhibit initiation of transcription
what are examples of hydrophobic signalling molecules
the steroid hormones oestrogen and testosterone
where do steroid hormones bind
to specific receptors in the cytosol or the nucleus
where does the hormone receptor complex bind to
the specific DNA sequences called hormone response elements (HREs).
what is influenced as a result of the hormone receptor complex binding to HREs
the rate of trasncription, with each steroid hormone affecting the gene expression of many different genes
where does the hormone receptor complex move to
the nucleus where it binds to specific sites on DNA and affects gene expression
