Fluorescence in situ hybridization

Question 1

This can be used for , particularly where QF-PCR is not available.

Answer 1

Fluorescence in situ hybridization

Question 2

Can be used to detect specific disease - associated chromosomal microdeletions or microduplications (such as the microdeletion at 22q11 associated with velocardiofacial syndrome) and to identify the chromosomal origin of chromosomal material in complex rearrangements.

Answer 2

Fish

Question 3

Possible uses of Fluorescence in situ hybridization:

Answer 3

Rapid detection of aneuploidy on interphase chromosomes in prenatal testing

Detect specific disease-associated chromosomal microdeletions or microduplications, e.g., microdeletion at 22q11 associated with velocardiofacial syndrome

Identify the chromosomal origin of chromosomal material in complex rearrangements