Enantiomers from Carbonyl Compounds Flashcards

1
Q

What reaction mixture is formed from the 2 enantiomers after reduction of carbonyl compounds with cyanide? What are its proportions in terms of ratios of enantiomers?

A
  • Racemic mixture
  • 50/50 since there is a 50/50 chance of the attack happening on either side
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2
Q

What enantiomer is formed when cyanide ions react with carbonyls?

A
  • :CN- attacks either side of the carbonyl
  • The 2 different sides can cause 2 different enantiomers to be formed
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3
Q

What happens in the racemic mixture in regard to plane polarised light?

A
  • Enantiomers in a racemic mixture rotate plane polarised light
  • But in opposite reactions
  • Since there is a 50/50 mixture, the opposite rotations cancel out
  • So no effect on plane polarised light in racemic mixtures
  • Ie. Optical rotation is 0
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4
Q

How can we test if mixtures are racemic?

A
  • If there is an effect on plane polarised light, then the sample is not racemic
  • If the sample contains enantiomers of chiral compounds and there is 0 effect on polarised light, then the reaction mixture must be racemic
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5
Q

What is Chiral C?

A

Carbon attached to 4 different species.

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