1.5 Neurotransmitters And Pharmacology

Question 1

Where does neurotransmission occur

Answer 1

Synapse

Question 2

How do rapid release rates (of vesicles) occur

Answer 2

Synaptic vesicles are filled with NT and DOCKED in the synaptic zone

Question 3

Neurotoxin targets

Answer 3

Vesicular proteins

Question 4

Alpha latrotoxin (neurotoxin)

Answer 4

Inc. release of NT - seizures

Question 5

Botulinum toxin

Answer 5

Stops everything - diaphragm freezes can’t breathe

Question 6

Receptor kinetics

Answer 6

Type of post synaptic receptor determines how fast the response is

Question 7

Ion channels-linked receptor

Answer 7

Fast response

CNS: glutamate, GABA
Neuromuscular junction: Ach at nicotinic receptors

Question 8

G protein -coupled receptors

Answer 8

Slow response

CNS and PNS: Ach at muscarinic receptors, dopamine, adrenaline, serotonin and neuropeptidea