Disorders Of Sexual Development Flashcards
-Define DSD?
-Factors to be considered while determining sex
-Schematic representation of the Development of Gonads?
1.Define
Female pseudohermaphroditism
Male Pseudohermaphroditism
True hermaphrodite
Gonadal dysgenesis
Classification of DSD (Hughes, 2008)
Female Pseudohermaphroditism:
Adrenogenital Syndrome
(Congenital Adrenal Hyperplasia)
Etiology
Clinical Presentation
Diagnosis at birth
Investigations
Management P. 372 of Datta.
45, XO Sex Chromosome DSD
Gonadal Dysgenesis (45, XO DSD)
Turner’s Syndrome:
Investigations
Management P.372
Structural Abnormality of X chromosome?
Pure Gonadal Dysgenesis or Gonadal Agenesis?
Mixed Gonadal Dysgenesis (45, X/46, XY DSD)
Klinefelter’s Syndrome (47, XXY DSD)
46, XY Disorder of Sexual Development:
Androgen Insensitivity Syndrome
(Testicular Feminization)
46, XY DSD ( Swyer Syndrome)
Complete Gonadal Dysgenesis.
Testicular Regression Syndrome.
_True Hermaphroditism_
OvoTesticular Disorder (46, XY DSD)