Heart failure/ACS Drugs

Question 1

Name an example of a short acting nitrate

When would it be used?

Answer 1

Glycaryl trinitrate

Acute angina and chest pain in ACS

Question 2

Name an example of a long-acting nitrate

Answer 2

Isosorbide mononitrate

Either
1. prophylaxis of angina if beta blocker/ CCB ineffective

Question 3

What are the contraindications to nitrate use?

Answer 3

severe aortic stenosis
hypotension

Important interaction: cannot be perscribed with phosphodiesterase inhibitors (e.g. sildenafil) tdue to hypotension