Pharmacology Flashcards

1
Q

Anticoagulant (Heparin, Enoxaparin, Fondaparinux)

A

Used in thrombotic disorders
Interactions: All herbal medications, NSAIDS
Therapeutic use: Stroke, Pulmonary embolism (sudden blockage in a lung artery),
Deep vein thrombosis (blood clots that form inside veins)

Complications: Toxicity, Hemorrhage, Neurological damage from hematoma- (collection of blood outside the blood vessels)

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2
Q

Antiplatelet
Aspirin, Abciximab, Clopidogrel, Dipyridamole

A

Therapeutic Use: Primary prevention of acute myocardial infarction, prevention of ischemic stroke or transient attack

Complications: GI effects (nausea vomiting, dyspepsia), Bleeding

Contraindications/Precautions: Renal and liver disease, older adults, pregnant, bleeding disorders

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3
Q

Thrombolytic Agents
(Alteplase)

A

Therapeutic Use: Given to dissolve thrombi by stimulating the conversion of plasminogen to plasmin (Enzyme that breaks down fibrin)

Goal: reestablish blood flow as quickly as possible, prevent/limit tissue damage

Main adverse effect: bleeding

Protamine sulfate is the antidote.

Contraindications: Hemorrhage, active internal bleeding

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4
Q
A
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