Heme Malignancies Flashcards

1
Q

Lymph nodes that are soft, tender, mobile but enlarged suggest…

A

inflammation/infection

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2
Q

Lymph nodes that are firm, rubbery, mobile and enlarged suggest…

A

lymphoma

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3
Q

Lymph nodes that are hard, fixed, non-tender suggest…

A

carcinoma

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4
Q

At what stage of hematopoiesis does lymphoma affect/occur

A

mature lymphocytes (B cells and mature T cells)

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5
Q

Describe leukemia

A

cancer of blood & bone marrow characterized by uncontrolled accumulation of malignant WBC

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6
Q

Describe the etiology of acute versus chronic leukemia

A

also myeloid vs lymphoid

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7
Q

Describe the difference in clinical presentation between acute and chronic leukemia

A
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8
Q

Describe the diagnosis of leukemia

A
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9
Q

Describe the risk factors for the different forms of leukemia (acute v chronic & myeloid v lymphoid)

A
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10
Q

Describe the etiology of acute myeloid leukemia and the common emergencies within

A
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11
Q

Describe the presentation of acute myeloid leukemia

A
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12
Q

Describe the presentation of tissue infiltration in AML

A
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13
Q

Describe the presentation of leukostasis in AML

A
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14
Q

Describe the presentation of disseminated intravascular coagulation in AML

A
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15
Q

Describe the presentation of tumor lysis syndrome in AML

A
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16
Q

Describe the treatment of AML

A
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17
Q

Describe the treatment for leukostasis in AML

A

leukapheresis & emergent initiation of chemo

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18
Q

Describe the treatment for DIC in AML

A

replace clotting factors and platelets & start chemo

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19
Q

Describe the treatment of tumor lysis syndrome in AML

A

hydrate, allopurinol to clear uric acid, dialysis as needed

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20
Q

Describe the etiology of acute lymphoblastic leukemia

A
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21
Q

Describe the presentation of ALL

A
22
Q

Describe the treatment for ALL

A
23
Q

Describe the etiology of chronic myeloid leukemia

A
24
Q

Describe the presentation of CML

A
25
Q

Describe the treatment for CML

A
26
Q

Describe the etiology of chronic lymphoid leukemia

A
27
Q

Describe the presentation of CLL

A
28
Q

Describe the treatment for CLL

A
29
Q

Describe the etiology of lymphoma (Hodgkin & Non-Hodgkin)

A
30
Q

Describe the presentation of lymphoma

A
31
Q

Describe the diagnostics for lymphoma

A
32
Q

Describe the staging of lymphoma

A
33
Q

Describe the etiology of myeloma

A
34
Q

Describe the etiology of monoclonal gammopathy of uncertain significance (MGUS)

A
35
Q

Describe the etiology of multiple myeloma

A
36
Q

Describe the presentation of multiple myeloma

A
37
Q

Describe the diagnosis of myeloma

A
38
Q

Describe the treatment for myeloma

A
39
Q

Describe the etiology of myelodysplastic syndromes (MDS)

A
40
Q

Describe the presentation of MDS

A
41
Q

Describe the diagnosis of MDS

A
42
Q

Describe the treatment of MDS

A
43
Q

Describe the etiology of myeloproliferative neoplasms

A
44
Q

Describe the presentation & complications of MPN

A
45
Q

Describe the diagnosis of MPN

A
46
Q

Describe the treatment of MPN

A
47
Q

Describe the etiology of aplastic anemia

A
48
Q

Describe the presentation & diagnosis of aplastic anemia

A
49
Q

Describe the treatment of aplastic anemia

A
50
Q

What are some complications of aplastic anemia

A

development of myelodysplastic syndromes or acute myeloid leukemia