Lecture 13 Part 3 - MC Flashcards
What is the primary role of HDL in the body?
A) To deliver triglycerides to peripheral tissues
B) To facilitate “Reverse Cholesterol Transport”
C) To synthesize proteins
D) To convert carbohydrates into energy
B
Why is HDL often referred to as ‘good cholesterol’?
A) Because it contributes to plaque formation
B) Because it removes cholesterol from tissues and takes it to the liver
C) Because it is involved in transporting glucose
D) Because it synthesizes bile acids directly
B
How does HDL initially appear when released from the liver?
A) Spherical and full of cholesterol
B) Discoidal and has very little cholesterol
C) Triangular and loaded with triglycerides
D) Oval and contains a high concentration of proteins
B
Which receptor is involved in the interaction between HDL and tissues?
A) LDL receptor
B) ABCA1 receptor
C) VLDL receptor
D) IDL receptor
B
What transformation does HDL undergo after collecting cholesterol from tissues?
A) It becomes more discoidal
B) It shrinks and becomes denser
C) It becomes spherical
D) It disintegrates
C
What enzyme is crucial in converting cholesterol into cholesterol esters within HDL?
A) Lipoprotein lipase (LPL)
B) Hepatic lipase (HL)
C) Lecithin-cholesterol acyltransferase (LCAT)
D) Pancreatic lipase
C
What is the function of the SR-B1 receptor in the context of HDL metabolism?
A) It binds to ApoB and allows triglycerides to be unloaded
B) It binds to ApoE and ApoA1 and allows cholesterol and esters to be unloaded
C) It synthesizes more HDL particles
D) It converts HDL into LDL
B
What happens to the HDL particle after it unloads cholesterol and other components via the SR-B1 receptor?
A) It becomes larger and more buoyant
B) It disintegrates
C) It shrinks
D) It converts into VLDL
C
