181 - Lyme Borreliosis

Question 1

What are the 3 stages of Lyme disease?

Answer 1

1- erythema migrans
2- annular cutaneous lesions/meningitis/neuritis/AV block/musculoskeletal pain
3- arthritis, encephalopathy, chronic polyneuropathy

Question 2

The first stage is __. After incubation period of - days, __ appear.

Answer 2

localized
3-32
erythema migrans (target sign)

Question 3

The second stage is __. Days-weeks after the EM appear, typical ___ symptoms may appear. Some weeks after __ symptoms may appear.

Answer 3

disseminated
CNS
cardiac

Question 4

During the 2nd stage, migratory __ pain is common. It usually lasts - in two locations simultaneously

Answer 4

musculoskeletal

days-weeks

Question 5

The 3rd stage is __. If left untreated _% of patients will develop __ for weeks-months in every location

Answer 5

persistent

oligoarthritic

Question 6

Leptospirosis diagnosis can be done in 3 ways:

Answer 6

cutaneous lesion culture
synovial fluid PCR
serology

Question 7

What is the recommended treatment for Lyme disease?

Answer 7

PO ABx, beside in neurological disease or AV block III

Question 8

Early disease should be treated for __ days. In adults: __, in children/pregnancy- __.

Answer 8

14
doxycycline
amoxicillin

Question 9

Doxycycline may cause- __ reaction

Answer 9

Jarisch Herxheimer

Question 10

Disseminated disease should be treated for __ days.

Answer 10

21

Question 11

In cases of arthritis treatment should last for __ days. If first line failed- treat with __ for 28 days. If it continues give __.

Answer 11

30
ceftriaxone
NSAID

Question 12

In cases of neurological disease- treat with __ for __ days.

Answer 12

ceftriaxone

28

Question 13

If wide PR or AV block appear- treat with ___ and __ monitoring

Answer 13

IV ceftriaxone

cardiac