(2) HC.4 Behandeling epilepsie Flashcards

1
Q

Basisprincipe anti-epileptica

A

verlagen prikkelbaarheid vd cel

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2
Q

Soorten anti-epileptica

A
  • prikkelbaarheid ion-kanalen verlagen (bv remmen Na-kanalen)
  • Versterken inhibitie (bv stimuleren GABA kanalen)
  • Remmen excitatie
  • Remmen transmitterafgifte
  • Remmen metabolisme
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3
Q

Medicatie
Remmen Na-kanalen

A
  • -ine
  • -azepine
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4
Q

Medicatie
Remmen Ca-kanalen

A
  • ethosaximide
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5
Q

Medicatie
Versterken GABA

A
  • benzodiazepines
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6
Q

Medicatie
Remmen excitatie

A
  • perampanel (AMPA remmer)
  • felbamaat (NMDA remmer)
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