2- Synaptic Plasticity Flashcards
A student is studying the nerve conduction velocity …… and the synaptic transmission occurs with central delay of 1.5 msec , calculate the number of synapses:
1.5 X2 = 3 synapses
A student is studying nerve conduction velocity …… calculate the central delay in pathway contain 3 synapses:
3\2 = 1.5 msec
Which of the following is a short and long term from pd placiticity ?
Sensitization
Which of the following causes loss of consciousness ?
interruption of cerebral circulation for 3-5 seconds
Which of the following causes irreversible brain damage?
interruption of cerebral circulation for 3-5 mints
Which of the following increases the synaptic transmission?
Hypocalcemia
Both hyperglycemia and hypoglycemia result in coma, explain.
- Hypoglycemia: Glucose is the preferable fuel of the brain, so hypoglycemia inhibits synaptic transmission.
- Hyperglycemia: increase the ketone bodies, causes acidosis result in increase in ionized Ca and decreases synaptic transmission
What are the characters of synaptic transmission?
1- Forward directions
2- Synaptic delay
3- Fatigues
4- Synaptic plasticity
What is the synaptic delay?
0.5 msec/synapse
What is the mechanism of the fatigue?
1- Exhaustion of pre synaptic vesicles due to repetitive stimulation
2- Depletion of neurotransmitters
3- Inactivation of post synaptic receptor (Down-regulation)
4- Gradual inactivation of the channels
The synaptic plasticity represents forms of?
Learning and memory
Forms of Synaptic plasticity?
1- Short (PTP, Habitation)
2- Long (LTP, Sensitisation)
3- LTD
The post tetanic potentiation is the basic mechanism for?
Immediate memory
What is the ionic basis of the post tetanic potentiation ?
Accumulation of Ca++ in the pre synaptic neurons
