2.1 Nucleic Acids Flashcards

0
Q

The pentose sugar in DNA is?

A

Deoxyribose

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1
Q

The pentose sugar in RNA is?

A

Ribose

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2
Q

What are mono nucleotides made of?

A

Pentose sugar
Nitrogen base
Phosphate group

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3
Q

What are the two types of nitrogen containing bases found in nucleic acids?

A

Purines

Pyrimidines

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4
Q

What is the enzyme that causes the two strands to break apart in DNA?

A

Helicase enzyme

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5
Q

Where does translation happen?

A

Cell surface of ribosomes

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6
Q

What is a codon?

A

A sequence of base pairs on the DNA or RNA is known as a codon.

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7
Q

What is a gene?

A

Usually defined as a sequence of bases on a DNA molecule coding for a sequence of amino acids in a polypeptide chain.

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8
Q

What is a mutation?

A

If a single codon is changed or misread during the process then the amino acid for which it codes may be different and so the whole polypeptide chain and indeed the final protein may be altered.

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9
Q

What is a catalyst?

A

A substance that speeds up a reaction without changing the substance produced and it is left unchanged at the end of the reaction.

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10
Q

Enzymes that work inside the cells are called?

A

Intercellular enzymes

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11
Q

How do enzymes work?

A

To lower activation energy and catalyst a reaction enzymes from a complex with the substrate or substrates of the reaction.

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12
Q

Lock and key hypothesis?

A

In protein structure of an enzyme there is an area called an active site which and a very specific shape. Only one substrate will fit into this area.

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13
Q

Induced fit hypothesis?

A

Once the substrate enters the active site the shape of that site is modified around it to form the active complex.

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14
Q

What do statins do?

A

Lower blood cholesterol levels. They block then enzyme in the liver than is responsible for making cholesterol and area specially effective at blocking the production of LDL’s.

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15
Q

Structure of an enzyme?

A

Enzymes are globular proteins with a 3d structure which is maintained by hydrogen ionic and disulphide bonds It has a specific active site which is complementary to the substrate where there is a specific amino acid sequence which is maintained by hydrogen bonds and hydrophobic interactions