INTRO

Question 1

PHASES of Healing

Answer 1

Inflammatory
Fibroplastic
Maturation

Question 2

Inflammatory

Answer 2

3-4 days post injury

protect, localize, prepare for healing

Question 3

Norepinephrine
Histamine
Leukotaxin

Answer 3

Vasoconstriction- limits blood loss
Vasodilation
Vasodilation

Question 4

Clotting process

Answer 4

platelets stick together, clotting CASCADE- stop of blood loss, FIBRIN patch- formation of scab

Question 5

Fibroblastic Repair

Answer 5

2-3 days, 2 phases 1) granulation 2) Fibroblastic

Question 6

granulation phase

Answer 6

growth of new tissue, new blood vessels, creation of fibrous tissue

Question 7

Fibroblastic Phases

Answer 7

fibrin clot forms Granulation Tissue (framework for tissue to grow), accelerated collagen production,
weak pink immature scar

Question 8

Maturation Remodeling Phase

Answer 8

3 wk-2 year, granulation tissue is replaced by new collage, tissue heals according to stress placed on it, Type III collagen replaced by Type I collagen

Question 9

Cartilage Healing

Answer 9

Articular- little healing ability

Fibrocartilage- 3 zone. RED- Great heal, RED/White- ok heal, White- no heal

Question 10

Nerve Healing

PNS vs CNS

Answer 10

PNS- once dead no regenerate, regenerate from partial tearing, 2-4mm a day

Question 11

Fracture Healing

Answer 11

1) Acute: 1 wk, hematoma forms, soft callus forms
2) Repair: 8-12 weeks, soft to hard callus, cartilage to bone (wk 3)
3) Remodeling: callus is replaced by trabecular bone, Wolff’s law

Question 12

Angiogenesis-

Answer 12

creating new blood vessel in injured area